Review: Metabo Flashcards
1
Q
Where is VLDL synthesized?
A
Liver
2
Q
What is PFK1 regulated by?
A
Product of PFK2, F26BP
3
Q
Is PFK2 glycolytic enzyme?
A
No but plays major role in glycolysis through F26BP regulation of PFK1
4
Q
Regulation of pyruvate kinase?
A
Activation: insulin, F16BP
Inhibition: Glucagon, epinephrine, ATP, Alanine
5
Q
What does lactate dehydrogenase deficiency cause?
A
Exercise intolerance
6
Q
Difference between HMG CoA synthase/reductase?
A
Synthase - converts AcCoA to ketone body
Reductase - converts AcCoA into malevolonate/cholesterol
7
Q
What does succinyl co A transferase do”?
A
- Convert ketone body to AcCoa allowing to use for energy
- Enzyme is not found in liver so liver cannot use for energy
8
Q
HDL?
A
- Good cholesterol
- Small in size
- Low in cholesterol []
- Is not oxidized
- Helps prevent LDL oxidation
9
Q
LDL?
A
- Higher level cholesterol
- Easily oxidized
- ## Larger than HDL
