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Metabolism > Cholesterol > Flashcards

Cholesterol Flashcards

1
Q

Main lipid in Chylomicron?

A

TAG

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2
Q

Main lipid in Chylomicron remnant?

A

TAG

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3
Q

Main lipid in VLDL?

A

TAG

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4
Q

Main lipid in IDL?

A

TAG & cholesterol

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5
Q

Main lipid in LDL?

A

cholesterol

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6
Q

Main lipid in HDL?

A

cholesterol

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7
Q

Main apoprotein in Chylomicron?

A

B-48 (A,C,E)

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8
Q

Main apoprotein in Remnant?

A

B-48 (A,C,E)

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9
Q

Main apoprotein in VLDL?

A

B-100 (A,C,E)

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10
Q

Main apoprotein in IDL?

A

B-100, E

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11
Q

Main apoprotein in LDL?

A

B-100

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12
Q

Main apoprotein in HDL?

A

A’s (C,E)

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13
Q

Function of Chylomicron?

A
  • Transports dietary TAG to adipose and other tissues
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14
Q

Function of Remnant?

A
  • Delivers remaining dietary TAG to liver.

- Exchanges TAG for CE from HDL; delivers CE to the liver

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15
Q

Function of VLDL?

A
  • Transports endogenously synthesized TAG to adipose tissue and to skeletal and heart muscle
  • Exchanges TAG for CE from HDL
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16
Q

Function of IDL?

A
  • Delivers remaining TAG and cholesterol to the liver.

- Exchanges TAG for CE from HDL. Delivers CE to the liver

17
Q

Function of LDL?

A
  • Delivers cholesterol to the liver and other cells, including steroidogenic cells
18
Q

Function of HDL?

A
  • Accepts cholesterol from peripheral cells, esterifies it, and transports the CEs to the liver
  • Exchanges CE for TAG in VLDL, IDL and chylomicron remnants.
  • Atheroprotective via enzymes such as paraoxonase that inhibit LDL oxidation
  • Serves as reservoir for circulating apoproteins (A,C,and E), which are transported to other lipoprotein particles
19
Q

What transports dietary lipids?

A

Chylomicrons

20
Q

What transports endogenous lipids?

A

VLDL, IDL, LDL

21
Q

What does Apo CII do?

A

Activates lipoprotein lipase

22
Q

What does apo A1 do?

A

Activates of lecithin:cholesterol acyltransferase (LCAT)

23
Q

What is Apo E a receptor for?

A

Remant

24
Q

What is Apo B 100 a receptor for?

A

LDL

25
Q

What is apo A1 a receptor for?

A

HDL

26
Q

What is B48 structural protein for?

A

Chylomicron

27
Q

What is B100 structural protein for?

A

LDL & VLDL

28
Q

What is A1 structural protein for?

A

HDL

Metabolism (17 decks)

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