SGPSS#13 Flashcards
1
Q
What diet should be fed in PDH deficiency?
A
- High fat diet
- Will increase ketogenesis which the brain can use for food since CAC is not working with glucose
2
Q
What else can increase blood lactate/pyruvate levels?
A
Arsenic
3
Q
What does aresenic do?
A
Inhibits PDH
4
Q
Symptoms of arsenic poisoning?
A
- Headache
- Diarrhea
- Confusion
- Drowsiness
5
Q
What can cause the following symptoms?
- Headache
- Diarrhea
- Confusion
- Drowsiness
A
Arsenic
6
Q
What is OAA generated pyruvate carboxylase used for?
A
To kick start the CAC
7
Q
What disease causes and enlarged stomach?
A
- Von Gerks
- G6P is accumulating in liver leading to enlarged stomach
8
Q
Where does beta oxidation occur?
A
Mitochiondira - fatty acids cannot enter mitochondria without carnitine
9
Q
Where does the energy needed for gluconeogenesis come from?
A
Fatty acid metabolism
10
Q
Where does energy for urea production come from?
A
Fatty acid metabolism
