Retinal Vein Occlusion Flashcards
What is retinal vein occlusion?
When a blood clot forms in the retinal veins & blocks the drainage of blood from retina
What is the central retinal vein for?
Draining blood from retina, it passes through optic nerve
What forms the central retinal vein?
4 branches come together to form the CRV
-Blockage of 1 causes problems in the area drained by that branch
What does blocking of retinal vein cause?
Pooling of blood in retina
This results in leakage of fluid & blood causing macular oedema and retinal haemorrhages
What do macular oedema and retinal haemorrhages result in?
Damage to tissue in retina & vision loss
Also leads to release of VEGF, stimulating revascularisation
Presentation of retinal vein occlusion?
Blockage of one of the retinal veins causes sudden painless loss of vision
Risk factors for retinal vein occlusion?
HT High cholesterol Diabetes (endothelial damage) Smoking Glaucoma -SLE
Investigation of retinal vein occlusion?
Fundoscopy
What will a fundoscopy show of retinal vein occlusion?
Flame & blot haemorrhages
Optic disc oedema
Macula oedema
Other tests for retinal vein occlusion?
Full history FBC (leukaemia) ESR BP Serum glucose
Management of retinal vein occlusion?
Immediate referral
In secondary care, aim to treat macular oedema & prevent complications
Options for for secondary care management?
- Laser photocoagulation
- Intravitreal steroids
- Anti-VEGF therapies
What is an intravitreal steroid example?
Dexamethasone intravitreal implant
Example of ant-VEGF therapies?
Ranibizumab
Bevacizumab
What is this one of the most common causes of?
Sudden, painless unilateral vision loss