respiratory system Flashcards
the nutritive vascularization of the lungs
by bronchial arteries; they branch out of the thoracic area, bringing to the lungs oxygenated blood
from the bronchial veins - leading the blood with Co2 to the superior vena cava
the functional vascularization of the lungs
is the small circulation; from the right ventricle -> pulmonary artery -> blood gives Co2 and receives O2 -> pulmonary veins going to the left atrium
Describe the act of inspiration
an active motor act;
with the respiratory muscles: lungs dilate passively due to the force of adhesion of the pleurae and so the pressure of the pulmonary air becomes lower than the atmospheric one
contraction of the external intercostal, super-costal muscles and of the diaphragm
describe the act of expiration
is a passive process;
respiratorys muscles relaxation -> the pressure inside the lungs increases and the air is expulsed
by internal inter-costal, right abdominal etc.
the frequency of the respiratory movements at rest is
of 16 breath/min in men and 18 breath/min in women
transportation of Co2 and O2 through the blood
Co2 dissolved as bicarbonates of Na and K, as carbonates and as carbamates (carboxyhemoglobin)
02 in free form or the combination with the hemoglobin, resulting in H2Co3 (HCo3-)
cellular tissue respiration by 2 processes:
by diffusion or redox reactions
The chemical redox reaction of the cellular tissue respiration is performed in stages
- the anaerobic degradation of glucose in the cytoplasm and oxidation of the fatty acids in the mitochondria
- decarboxylation in the Krebs cycle from mitochondria with release of Co2, H2o and H+
- the transfer of H+ in the electron transporting chainunti molecular O2
- ADP phosphorylation and electron transporte produce energy ATP
(with the help of the enzymes dehydrogenase and oxidase in the mitochondria)
ventilatory debt represents
the quantity of air passing through the lungs in one minute
the product of the current volume and the respiratory frequency -> in normal conditions: 8l/min
the nervous regulation of the breathing
the primary inspiratory and expiratory centers located in the medulla
and the apneustic and pneumotaxi centers located in the pons
Funktion of the apneustic and pneumotaxi centers
the apneustic centre has continuous excitatory action on the inspiratory action
By inspiration -> Impules with inhibitory effect on the inspiratory and apneustic centers
humoral regulation of the breathing by
Co2 concentration -> acts directly at the respiratory centers
reduction of 02 concentration -> weaker stimulation of the respiratory centers by reflex mechanisms through the chemoreceptors and of the carotid sinus and aortic cross
the extra pulmonary air ways are the
nasal Gosse, Pharynx, Larynx, trachea and the main bronchi
the total pulmonary capacity (TPC)
5000mL
is the sum of the vital capacity and residual volume
the vital capacity consists of
current volume, reserve inspiratory volume and the reserve expiratory volume
is in total 3500mL
The reserve inspiratory volume (RIV) is
a supplementary air volume which my be inhaled over the current volume
is about 1500mL
the reserve expiratory volume (REV) is
a supplementary amount of air which my be exhaled after a forced exhalation, after exhaling a current volume
is about 1500 mL
the residual volume is
the air volume that remains in the lungs even after a forced exhalation
is about 1500 mL
the pleural pressure is
the pressure form the space between the visceral pleura and the parietal one
fluctuates with the breathing phases
the alveolar pressure is
the pressure from the interior of the pulmonary alveoli+
in a state of rest when the glottis is open, the air does not circulate between the lungs and the atmosphere
number of lobes and segments of the lungs
right lobes: 3 (10 segments)
left lobes: 2 (9 segments)
pulmonary haematosis
is the oxygenation of the blood at the level of the alveolar capillaries
at the alvelar-capillary membrane
emphysema
a complex pulmonary process, which is obstructive and destructive
consequence of overlong smoking
(alveoli are damaged)
influenza
acute respiratory viral infection
caused by the influenza virus
contagious disease with seasonal charakter
asthenia is
pathological reduction of the capacity of physical and psychical effort
fatigue
the alveolar-capillary membrane compromises the
pulmonary interstice alveolar epithelium surfacant capillary endothelium alveolar basal membrane (fibro-elastic) capillary basal membrane