hemostasis Flashcards
3 phases of the hemostasis
vascular-platelet (2-4min), plasmatic (4-8min) and thrombosis-dynamic (2-24h)
the vascular platelet time consists in
vasoconstriction of the vascular wall, adherence of the platelets to the wound (aggregation of the thrombocytes)
they agglutination and formation of a platelet thrombus
viscous metamorphosis of the thrombocytes
also called temporary hemostasis
the plasmatic time consists in
the thromboplastin formation, the thrombin formation and the fibrin formation, which cause the blood coagulation
describe in detail the plasmatic time
the clotting factors are activated which leads to the formation of Fibrin from inactive fibrinogen plasma protein (the activation of fibrin is caused by thrombin) –> forming the blood clot “fibrin insoluble net”
the thrombo-dynamic time consists in
retraction of the clot by expulsing the serum, decomposition of the clot (fibrinolysis), removal of the clot and returning the circulation
polyglobulia is
the stable growth of the red blood cells
humans living in high altitudes or having some lung disease
anemia is
the reduction of red blood cells
diapedesis
the leukocyte passage through the walls of the capillary endothelium in the intercellular areas
leucopoiesis in which areas
red bone marrow (for granulocytes and monocytes) and in the spleen, thymus and lymph nodes (for lymphocytes)
active immunisation (vaccination)
attenuated oder killed pathogens
causing the production of specific antibodies
long time protection
passive immunisation (vaccination)
containing readily formed antibodies
short time protection (2-3 weeks)
agglutinogen means what? in is where found?
is the antigen (A and B) and found on the red cells
agglutinin means what? and is where found?
the antibodies (Alfa: anti-A, oder beta: anti-B) found in the plasma
Megloblastic anemia
production of some erythrocytes that are bigger than normal with altered form
due to disturbances of vitamin B12 or folic
absorption
(DNA Synthesis is impaired)
