endocrine system Flashcards
hormones of the adenohypohysis of the pituitary gland
somatropin hormone (STH) and tropic glandular hormones (adrenocorticotropic hormone (ATCH) thyrotrope hormone (TSH) gonadotropic hormone folicullostimulating hormone (FSH) luteinizing hormone (LH) luteotropic hormone (LTH) or prolactin (PRL)
function of the somatropin hormone
growth of entire body (cell development, synthesis of proteins, lipids oxidation)
hyperglycemic role
- hypersecretion prior to puberty: gigantism
- after puberty: acromegaly (excrementies, face bones, lips, viscera)
- hyposecretion: pituatry dwarfism (infantilism)
hormones of the neurohypophysis of the pituitary gland
Speicherung des antidiuretic hormone (ADH/vasopressin) and oxytocin (beides vom ANTERIOR hypothalamus gebildet)
function of the ADH/vasopressin
volume of the extracellular fluids in the body; stimulation of water absorption at renal level antidiuretic effect: reducing the loss of water in urine; large dose -> vasoconstriction = high blood pressure; causes hyperglycemia; stimulates the intestinal peristalsis
function of oxytocin
contractions of the pregnant uterus + lactation
hormones of the thyroid gland
thyroxin (T4) + triiodothyronine (T3)
function of T4 and T3
calorigenic effect (increase of basal membrane), cellular growth, protein catabolism
- hyposecretion: in children thyroid dwarfism, endemic goiter, myxedema
- hypersecretion: Basedows disease (exophthalmia)
hormones of the parathyroid gland
parathormone and Calcitonin (regulation only made humorally)
function of the parathormone
increase of the calcemia (high Ca), reducing the phosphatemia (low P) and osseous demineralizing (osteoclasts)
function of the Calcitonin
reducing the calcemia (low Ca), increasing the phosphatemia (high P), normal mineralization of the bones
removal of the parathormone leads to
tetany (unvoluntary contraction of the muscles, sensitive, nervous, trophic and visceral disorders) due to the lack of calcium
hormones of the CORTICAL adrenal
mineralcorticoids (aldosterone), glucocorticoids (cortisol) and sexual steroid hormones
hormones of the MEDULLAR adrenal
adrenalin and norarenalin
function of the aldosterol
mineral metabolism regulation: reabsorption of Na and K elimination at the distal tubules (high Na and low K; high blood pressure), acid-base-balance + osmotic pressure; hyposecretion: acidosis
- regulation of secretion: by ATCH and Renin
function of glucocorticoids (cortisol)
glucogenesis (synthesis of cabohydrates); protein + lipid metabolism, antiflammatory role, stimulus: ACTH
over hypothalamic-pituatry-cortical-adrenal system
Funktion of adrenalin
gylcogenoysis (decomposition of glucose), hyperglycemia (high Glucose concentration), mobilization of the fats, tachycardia, vasoconstriction
- stimulation of ARAS activity (cortical alert)
hormones of the endocrine pancreas
insulin and glucagon
function of insulin
depositing glucose as glycogen (lowering the glucose levels in the cells); carbohydrates into lipids, protein synthesis; regulation made by vagal parasympathetic impulses depending on the glycaemia
- hyposecretion: diabetes mellitus
hyperglycemia (high levels of glucose in the blood)
glycosuria (excretion of glucose in the urine)
polyuria (excessive large production of urine)
polydipsia (needs of large quantity of water)
polyphagia (high consume of food with loss of weight) - hypersecretion: hypoglecima (low levels of glucose)
function of melatonin
secretion from the epiphysis, regulates the day and nigh-rhythm, inhibitory action on sexual glands + hypoglycemic role (acts on hypothalamus-pituatry axis)
- by light stimulation -> reduction of melatonin
function of the thymus
lymphoid organ, involutes after puberty; thyme hormones: antidondatropin effects (inhibitory action on sexual glands); T-Lymphozytes are differentiated and specialized
hypersecretion of glucocorticoids causes
Cushing syndrome, generalized osteoporosis, reduction of the muscular mass and hyperglycemia
adrenocorticotropic hormone or corticotropin (ACTH) has which function
stimulates the growth of the portico-adrenal glands,
hypersecretion => hypertrophy of the cortico-adrenal and hypersecreting of its hormones (metabolic disorders)
the luteinizing hormone (LH) causes
the ovulation and appearance of the yellow body and in men stimulates the secretion of the androgen hormones
the luteotropic hormone (LTH) or prolactin stimulates
the secretion of the yellow body and lactate secretion + no effects on men