Respiratory Embryology Flashcards
Where does the lung bud originate from?
Cranial end of the gut tube
Endoderm will form the?
Lining of the respiratory treee
Lung grows into _____ which will afterwards be known as visceral ______
mesoderm
mesoderm
Mesoderm will form visceral mesoderm and?
All smooth muscle and cartilage within the lungs and trachea
Initially there is a lot of communication between the respiratory and digestive tract. How do these separate?
Indentations of growth inwards (ridges) will meet and fuse allowing complete separation
The lung bud divides to form?
The right and left lung
Secondary buds make up?
the main bronchi
What is a fistula?
An abnormal or surgically made passage between a hollow or tubular organ and the body surface, or between two hollow or tubular organs
Failure of division can result in a ______ between the oesophagus and trachea
fistula
What is the most common respiratory congenital defect?
Tracheooesophageal fistula and oesphageal atresia?
What is oesophageal atresia?
Blind-ending oesophagus
What happens between the 26th day and Week 6 (embryonic phase) of respiratory tract embryology?
Respiratory diverticulum forms
Initial branching to give lungs, lobes and segments
What happens between week 6 and 16 (pseudo glandular phase)?
14 more generations of branching
Terminal bronchioles
What happens between week 16 and 28 (canalicur phase) ?
Divides into at least 2 respiratory bronchioles which divide into 3-6 alveolar ducts
What happens between week 28 and 36 (saccular phase)?
Terminal sacs form
Capillaries establish close contact
