Cardio Histology Flashcards
What are the three layers of blood vessels?
Tunica intima
Tunica media
Tunica adventitia
What make sup the tunica intima?
Single layer of squamous epithelial cells (endothelium) supported by basal lamina and connective tissue layer
What makes up the tunica media?
Smooth muscle of varying amounts
In muscular arteries the tunica media and adventitia are separated by?
An external elastic membrane
What is the tunica adventitia made of?
Supporting connective tissue
Elastic (large) arteries with elastic fibres in their tunica media have?
Elastic recoil
How are large elastic arteries supplied with blood?
Half obtain nutrients from lumen
Half have their own blood supply (vaso vasorum)
What make sup the walls of arterioles?
Thin tunica media
Almost no adventitia
What makes up the wall of capillaries?
Endothelium ü basal lamina
Often have pericytes at intervals just outside the basal lamina
What are pericytes?
Connective tissue cells with contractile properties
What are the 3 types of capillaries?
Continuous
Fenestrated
Sinusoidal/Dicontinuous
What are the features of fenestrated capillaries?
Pores in wall
Where are fenestrated capillaries found?
Mucosa of the gut, endocrine glands, and glomeruli of the kidneys
What are features of sinusoidal capillaries?
No bassal lamina Large gaps (macromolecules and some cells can pass
Where are sinusoidal capillaries found?
Liver
Spleen
Bone marrow
What makes up the walls of post-capillary venules?
Endothelial cells with pericytes or smooth muscle
Postcapillary venules are important exchange sites for things like?
Immune cells
Microvascularly, how is the small arteriole connected to post-capillary venue?
Through metaarteriole network, thoroughfare channels and capillaries
What are pre-capillary sphincters composed of?
Smooth muscle
Smooth muscle in pre-capillary sphincters help to control?
Flow through network