Cardio Histology Flashcards

1
Q

What are the three layers of blood vessels?

A

Tunica intima
Tunica media
Tunica adventitia

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2
Q

What make sup the tunica intima?

A

Single layer of squamous epithelial cells (endothelium) supported by basal lamina and connective tissue layer

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3
Q

What makes up the tunica media?

A

Smooth muscle of varying amounts

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4
Q

In muscular arteries the tunica media and adventitia are separated by?

A

An external elastic membrane

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5
Q

What is the tunica adventitia made of?

A

Supporting connective tissue

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6
Q

Elastic (large) arteries with elastic fibres in their tunica media have?

A

Elastic recoil

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7
Q

How are large elastic arteries supplied with blood?

A

Half obtain nutrients from lumen

Half have their own blood supply (vaso vasorum)

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8
Q

What make sup the walls of arterioles?

A

Thin tunica media

Almost no adventitia

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9
Q

What makes up the wall of capillaries?

A

Endothelium ü basal lamina

Often have pericytes at intervals just outside the basal lamina

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10
Q

What are pericytes?

A

Connective tissue cells with contractile properties

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11
Q

What are the 3 types of capillaries?

A

Continuous
Fenestrated
Sinusoidal/Dicontinuous

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12
Q

What are the features of fenestrated capillaries?

A

Pores in wall

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13
Q

Where are fenestrated capillaries found?

A

Mucosa of the gut, endocrine glands, and glomeruli of the kidneys

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14
Q

What are features of sinusoidal capillaries?

A
No bassal lamina 
Large gaps (macromolecules and some cells can pass
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15
Q

Where are sinusoidal capillaries found?

A

Liver
Spleen
Bone marrow

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16
Q

What makes up the walls of post-capillary venules?

A

Endothelial cells with pericytes or smooth muscle

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17
Q

Postcapillary venules are important exchange sites for things like?

A

Immune cells

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18
Q

Microvascularly, how is the small arteriole connected to post-capillary venue?

A

Through metaarteriole network, thoroughfare channels and capillaries

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19
Q

What are pre-capillary sphincters composed of?

A

Smooth muscle

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20
Q

Smooth muscle in pre-capillary sphincters help to control?

A

Flow through network

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21
Q

What makes up the wall of a vein?

A

Tunica intima, media and adventitia

22
Q

The tunica media in veins is ____ relative to lumen size

A

Thin

23
Q

Valves in medium/large veins are?

A

Inward extension of tunica intimal + small layer of connective tissue to ensure unidirectional flow

24
Q

What are the 3 layers of the heart

A

Endocardium
Myocardium
Epidacridum

25
Q

The endocardium lines the?

A

Inner heart surface including valves

26
Q

What make sup the endocardium

A
Endothelium
Basal lamina
Thin collagen fibre layer
Denser connective tissue layer
(subendocardium in some areas)
27
Q

Subendocardium is?

A

Loose connective tissue containing small blood vessels and nerves and the branches of the impulse conducting system

28
Q

The myocardium is a?

A

Thick middle layer

29
Q

What makes up the myocardium?

A

Bundles/layers of contractile cardiac fibres

Individual muscle fibres surrounded by collagenous connective tissue with capillary network

30
Q

The contractile cardiac fibres are boiled together by?

A

Intercalated discs

31
Q

The epicardium is an ______ on heart surfaces

A

outer

32
Q

What makes up the epicardium?

A

Single layer of flattened epithelium (mesothelium
Basal lamina
Fibro-elastic tissue
+ adipose tissue in some areas

33
Q

What are the two parts of the pericardium?

A

Fibrous and serous pericardium

34
Q

What is the fibrous pericardium?

A

Sac of tough fibrocollagenous connective tissue

35
Q

What is serous pericardium?

A

Layer of simple squamous epithelial cells + basal lamina & connective tissue

36
Q

Srous pericardium is a layer of?

A

Simple mesothelium, basal lamina and connective tissue

37
Q

What are the two types of serous pericardium?

A

Parietal and serous

38
Q

What does parietal serous pericardium line?

A

Inner fibrous pericardium

39
Q

Visceral serous pericardium covers?

A

Surface of heart

40
Q

What is the fibrous skeleton of the heart formed by?

A

Bands of fibrous connective tissue around heart valves, between atria and between ventricles

41
Q

What is the function of the fibrous skeleton of the heart?

A

Support and attachment point for cardiac muscles

Electrically isolates atria and ventricles

42
Q

What makes up the heart valves?

A

Outer endothelial layer with basal lamina
Collagen layer and elastin fibres
Core dense connective tissue (=lamina fibrosa) in continuity with fibrous skeleton

43
Q

What anchors leaflets of mitral/tricuspid valves in ventricular wall by collagenous strands (chord tendinae) which merge with lamina fibrous?

A

Papillary muscles

44
Q

Where are purkinje fibres found?

A

Subendocardium

45
Q

Purkinje fibres are ____ than normal cardiac myocytes

A

larger

46
Q

What are characteristics of purkinje fibres?

A
Abundant glycogen
No T-tubules
No intercalated discs 
Sparse actin and myosin filaments 
Appear very pale histologically
47
Q

Lymphatic vessels begin as?

A

Blind sacs

48
Q

Where do lymphatic vessels being?

A

Interstitial spaces

49
Q

Lymphatic vessels absorb interstitial fluid containing?

A

Ions
Lipids
Protein
Occasional cells

50
Q

The lymphatic system doesn’t have a pump. How is fluid moved?

A

Fluid generates hydrostatic pressure
Contraction of nearby muscles
Valves ensure unidirectional flow

51
Q

What is the function of the lymphatic system?

A

Drain excess tissue fluid (lymph) and pass it through lymph nodes