respiratory ch.5 Flashcards
lung cancer
begins in the lungs and is most common in smokers
lung cancer patho
- complex
- dysplasia in lung epithelial tissue
- exposure to carciogens can lead to genetic mutation and affect protein synthesis
- disruption of the cell cycle which causes carcinogenesis
lung cancer etiology
- caused by repeaed exposure to carcinogens (especially cigarette smoke)
- exposure to radon gas (second leading cost)
- occupational exposure: paving, roofing, painting and chimney sweeping
treatments of lung cancer
depends on stage
- quit smooking
- medications: chemo, targeted therapy, immunotherapy
- surgery: pulmonary lobectomy, wedge resection
- medical procedures: radiation, thoractomy
diagonsis of lung cancer
two types of lung cancer: small cell lung cancer and non small cell cancer
- x-ray
- ct
- sptum cytology
- tissue biopsy
lung cancer clinical manifestation
- dyspnea
- chest pain
- anemia
- persistent cough or chance in usual cough
- frequent respiratory infection
- airway obstruction
stage of lung cancer
- stage 1: invaded underlying lung tissue
- stage 2: neighboring lymoth nodes
- stage 3A: lungs to lympth nodes in center of cest
- stage 3B- lungs to lympth node in areas of the collarbone, heart, blood vessels, trachea, and esophagus
- stage 4: spread to other parts of body, such as liver bones or brain
lung cancer prevention
- stop smoking
- second hand smoke
- family history
- hiv infection
- environmental risk factors
- beta carotene supplements in heavy smokers
normal oxygen levels
80-100 mm hg
oxygen levels with arf
oxygen can be dangerously low (less than 50mm hg) which damages the nervous system, or CO2 levels become dangerously high (greater than 50 mm HG) leading to respiratory aciddosis which triggers vaso constriction causing cardiac arrest
patho of respiratory failure
respiratory failure happens when the capillaries or tiny blood vessels surrounding your air sacs cant properly exchange carbon dioxide for oxygen
etiology of respiratory failure
COPD, asthma, ARDs, amyotropic lateral sceloris, alcohol or drug overdose, and spinal cord injury
clinical manifestations of respiratory failure
shallow respiration headache tachycardia dysrhythmias lethargy confusion
diagnosis of respiratory failure
physical examination chest x-ray electrocardiogram cbc abg (arterial blood gases)
treatment of respiratory failure
- oxygen therapy
- endotracheal intubation with ventilation support
- bronchodilators
- antibiotics
- corticosteroids
- treatment of emboli
asthma clinical manifestations
- Shortness of breath.
● Chest tightness or pain.
● Wheezing when exhaling, which is also a common sign of asthma in kids.
● Trouble sleeping caused by shortness of breath, coughing or wheezing.
● Coughing or wheezing attacks that are worsened by a respiratory virus, such as a cold or
the flu.
● being too breathless to eat, speak or sleep.
● breathing faster.
● a fast heartbeat.
● drowsiness, confusion, exhaustion or dizziness.
● blue lips or fingers.
● fainting.
patho of asthma
- inflammed airways react to environmental triggers such as smoke, dust, pollen
- airway epithelial cells, which are the first line of defense against inhaled pathogens are partiles, initiate airway inflammation and produce muscous
- leads to coughing and breathign dificulties
- airway narrows
- result of immune response in the bronchial airways
- in response bronchi contract into spasm
genetic predisposition of asthma
- more than 100 genes associated with allergic asthma
- offspirng of asthmatic parents
- ORMDL3 gene associated with childhood onset
- HLA-DQ gene was related to later onset asthma
treatment of asthma
- symptoms controlled
- inhaled and systemic corticosteroids: supress airway inflammation
- bronchiodilators
- leukitriene
- mast cell stabilizer
- anticholinergics
diagnosis of asthma
- lung function test
- chest or sinus x ray
pt teaching of asthma
- properly teach pt. how to use inhaler
- take asthma medication directly as your provider tells u
- be sure to always have a quick- relief inhaler
- watch for early changes of symptoms getting worse by using a peak flow meter
- use dust proof covers
- dont smoke
- try to keep window closed during pollen seasons
what is pneumonia
- an infection that inflamed the lungs and impairs gas exchange
- air sacs fill with fluid causing cough and difficulty breathing
patho of pneumonia
development occurs when a pathogen reaches the alveoli and host defesnes are overwhelmed by microorganisms or by the inoculum size
pneumonia diagnosis
- ineffective airway clearance
- impaired gas exchange
- ineffective breathing pattern
- risk for infection
- acute pain
pneumonia etiology
- infectious agents
A: bacteria and viruses that are usually inhaled
- infection gets into lungs causing inflammation
- steptococcus pneumoniaw is responsible for most cases of pneumonia
B: fungi
2. injurious agents A: aspiration - gastric contents B: endotracheal intubation C: smoke - inhalation of smoke or chemicals
clinical manifestations pneumonia
- hypoxemia
- cough
- fever
- rapid and shallow breathing
- loss of appetite
- abnormal lung sounds
- fatigue
- chest pain
- dehydration
- clammy skin
- difficult or labored breathing