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Pharm Block 2 > Respiratory > Flashcards

Respiratory Flashcards

1
Q

B2 agonists short acting - acute management

A

Salbutamol
albuterol
terbutaline
metaproterenol

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2
Q

B2 agonists long acting - used for prophylaxis

A

salmeterol

formeterol

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3
Q

stimulate B2 receptors
increase cAMP
decrease muscle tone
bronchial smooth muscle relaxation

A

Salbutamol
albuterol
terbutaline
metaproterenol

salmeterol
formeterol

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4
Q

ADR: usually have minimal to no ADR, fine tremors, dizziness, restlessness, agitation

A

B2 agonists

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5
Q

antagonize the actions of leukotrienes
inhibit brinchoconstriction
decrease microvascular leakage and mucus production
inhibit influx of basophils and lymphocytes into airways

A

leukotriene modulators (LOX)

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6
Q

leukotriene receptor blockers

A

montelukast

zafirlukast

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7
Q

leukotriene synthesis inhibitors

A

zileuton - blocks LOX

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8
Q 
Bronchodilation
CNS stimulant 
CVS stimulant 
inhibit PD4 in bronchial mucosa
antagonism of adenosine receptors
A

Theophylline
Theobromine
caffeine

all are xanthine deriavtives

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9
Q

block M3 receptors
increase mucociliary clearance
used in nebulizers

A

ipratropium
ocitropium
tiotropium

atropine cannot use cause it blocks mucus clearance

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10
Q

Glucocorticoids

A

beclomethasone
fluticasone
triamicinolone
budesonide

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11
Q

modulate cytokine and chemokine production
inhibit eicosanoid synthesis
inhibit accumulation of mast cells
decrease vascular permeability

A

Glucocorticoids

beclomethasone
fluticasone
triamicinolone
budesonide

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12
Q

ADR: most common is dysphonia and oral candidiasis

A

beclomethasone
fluticasone
triamicinolone
budesonide

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13
Q

mast cell stabilizers from degranulation
inhibit further release of inflammatory
mediators from mast cells

A

sodium cromoglicate

nedocromil sodium

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14
Q

dry antitussives - opioids

act on medullary anti cough center

A

codeine
pholcodeine
morphine

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15
Q

dry antitussives - non opioid

act on medullary anti cough center

A

noscapone

dextromethorphan

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16
Q

dry antitussives - antihistamine

act on medullary anti cough center

A

promethazine
chlorpheniramine
diphenhydramine

17
Q

wet expectorants
increase tracheobronchial secretions
breaks disulfide bonds in vicid mucus

A 
sodium and potassium citrate
K iodide
ammonium salts
guaiphenesin
bromhexine
carbosyteine
acetyl cysteine

Pharm Block 2 (22 decks)

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