Other Diuretics Flashcards
extracts water by osmotic effect working in the PCT & descending LOH
mannitol - osmotic diuretic
treats: cerebral edema, glaucoma, acute renal failure
mannitol
SE: extracellular volume expansion prior diuresis, used carful in heart failure, dehydration, hyperkalemia, hypernatremia, hyponatremia
mannitol
activate water reabsorption from collecting duct by activating V2 receptors
increases cAMP causing insertion of AQ2 ch on luminal surface
treats: neurogenic DI
ADH agonists: ADH & desmopressin
inhabit action of ADH & block insertion of water channels on luminal surface
treats: SIADH (abnorm ADH secretion) causes water retention, hyponatremia
ADH antagonists: Demeclocycline, Lithium, Conivaptan
Ca2+ = 0 HCO3 = + K+ = + Mg2+ = ++ Na+ = +++ H+ = 0
mannitol - osmotic diuretic