H1 & H2 Antihistamines & Ergots

Question 1

1st gen sedating H1

Answer 1

doxylamine
Diphenhydramine 
chlorpheniramine
promethazine
cinnarixine
hydroxyzine
astemizole

Question 2

antagonize histamine induced bronchoconstriction, uticaria

treatments of allergies, sedating, can prevent motion sickness

Answer 2

1st gen H1

Question 3

morning sickness given with vit 6

Answer 3

doxylamine

Question 4

motion sickness

reduces tremors and rigidity seen in Parkinsonism

Answer 4

Diphenhydramine

Question 5

cough suppressant

Answer 5

chlorpheniramine

Question 6

anti emetic

reduce tremors and rigidity seen in Parkinsonism

Answer 6

promethazine

Question 7

treats veritgo

Answer 7

cinnarixine

Question 8

ADR: sedation, confusion, motor incoordination, alcohol will increase intensity; anticholinergic - dry mouth, constipation, blurry vision, urinary hesitancy

Answer 8

1st gen H1

Question 9

treatments for allergies

2nd gen H1

Answer 9

loratadine
fexofenadine
cetirizine
azelastin

Question 10

produced by fungus clavicles purpurae
partial agonist to alpha & 5HT2 receptor
SE: nausea, vomit, diarrhea, prolong vasoconstriction - ischemia and gangrene
Contraindications: coronary ischemia and pregnacy

Answer 10

Ergot Alkaloids

Question 11

ergots that work on CNS

Answer 11

LCD
bromocriptine
pergolide

Question 12

ergots that cause uterus to contract and used in OB bleeding and post part hemorrhage

Answer 12

ergonovine

ergotamine

Question 13

ergots that cause blood vessels to contract

Answer 13

ergotamine

methysergide

Question 14

used in hyperprolactinemia

Answer 14

bromocriptine

pergolide

Question 15

ergot used in parkinsons

Answer 15

bromocriptine

Question 16

ergot used in carcinoid tumor

Answer 16

methysergide

Question 17

ergot used in acute attack of migraine

Answer 17

ergotamine + caffeine