Respiratory Flashcards
Ventilation
flow of air into and out of the lungs
Perfusion
flow of blood through pulmonary cappillaries
Diffusion
Transfer of gases between the alveoli and pulmonary capillaries
Anatomic dead space
volume of air in the conducting airways (nose, trachea) that is moved with each breath but does not participate in gas exchnge
Alveolar dead space
air contained in the lung which does not participate in gas exchanged
Physiologic dead space
sum of anatomic and alveolar dead spaces
Shunting
the movement of blood from the right side of the heart to the left side of the heart without being oxygenated
Physiologic shunting
occurs when there is impaired movement of air (ventilation) or blood flow (perfusion)
Anatomic shunt
occurs when blood moves from the venous to the arterial side of the circulation without moving though the lungs
V-Q mismatch
occurs when there is a perfusion without ventilation or ventilation without perfusion
V-Q ratio when perfusion is without ventilation
low, atelectasis
V-Q ratio when ventilation is without perfusion
high, PE
pO2
the level of dissolved oxygen in plasma
what happens to hemoglobin saturation when it leaves the left side of the heart?
it drops
Oxygen-Hemoglobin dissociation curve when it shifts to right
increase in tissue metabolism (reduced affinity of hemoglobin for oxygen) d/t fever, acidosis, pulmonary insufficiency, severe anemia, exercise!
Oxygen-Hemoglobin dissociation curve when it shifts to left
decrease in tissue metabolism (increased affinity of hemoglobin for oxygen) d/t alkalosis and decreased body temp
Dorsal group location and function
located in medulla and controls inspiration
ventral group location and function
located in medulla and active when an increase in respirations is needed
Pneumotaxic center location and function
located in upper pons and can turn respirations off, controls rate and resp volume
Apneustic center location and function
located in lower pons and can prolong inspirations
chemosensitive center and what will happen if Ph is low?
are affected by the pH in CSF, if Ph low it will increase rest
Parasympathetic system
acetylcholine NT with muscarinc receptors ex. bronchoconstriction, pulmonary vasodilation
sympathetic system
epinephrine and norepinephrine NTs with B2 adrenergic receptors ex. Broncial smooth muscle relaxation, pulmonary vasoconstriction
lung stretch receptors location and function
in smooth muscle, respond to changes in pressure, control the stretch of a lung
lung irritant receptors location and function
located between airway epithelial cells, respond to irritants and causes airway constriction with rapid shallow breathing
lung Juxtacapillary receptors (J-recptors)
located in alveolar wall, responsible for rapid shallow breathing associated with pulmonary edema or embolism
The effects of gas exhange on pna
there is impaired diffusion of oxygen into cappillaries which causes hypoxemia, HR tachy, respiratoy alkalosis d/t stimulation of pulmonary receptors, hypercapnia
congestion phase of pna
4-24 hours, initial inflammatory response kicks in
red hepatization phase of pna
48 hours, extravasation of RBCs, fibrin into alveoli, tissue is firm and red
Gray hepatization phase of pna
72 hours-1 wk, fibrin accumulates and granulates
s/s of pna
increased HR, increased temp, rales, rhonchi (mucus in bronchi), decreased breath sounds over consoliation, E to A changes, dull percussion , resp alkalosis
Bacterial pna
acute, bacterial infection of lung, more common in adults than children
which bacteria is responsible for community acquired bacterial pna?
streptococcus pneumoniae or Haemophilus influenzae
which bacteria is responsible for hospital acquired bacterial pna?
gram negative rods like pseudomonas or gram positive like staph
which is more prevalent, community or nosocomial bacterial pne?
community
viral pna
inflammatory disease of lungs
viral pna causes
flu, RSV, Cytomegalovirus, varicella, Rubeola
Mycoplasma pna
acute interstitial pna caused by extensive infection of lungs and bronchi of lower lobes
how often do we see mycoplasma pna? and in which age group?
epidemics occur every 4-5 years, in men more than women, prevalent in children
what will WBC look like with mycoplasma?
normal
Bronchiolitis and which age group?
inflammation of bronchioles, out pouching, usually seen in babies
Bronchiolitis causes
viral, chlamydia, eye, nose inoculation, day care exposure
Bronchiolitis s/s
anorexia, cough, cyanosis, expiratory wheezing, fever, inspiratory crackles