Respiratory Flashcards
These two structures extend to end of bronchi?
Cartilage and goblet cells
Type of cells in terminal bronchiole?
pseudostratified ciliated columnar cells
Smooth muscle of the airway wall stops at?
Terminal bronchiole
Smooth muscles helps sweep mucous out of lungs
Respiratory zone of lung contains what type of cells?
cuboidal cells in respiratory bronchioles and then squamous cells up to alveoli– NO CILIA
These cells secrete surfactant?
Lamellar bodies of type 2 pneumocytes
2 ways to increase surfactant of fetus? dec?
Corticosteroids or thyroxine inc surfactant. Insulin decreases surfactant
What are clara cells?
nonciliated columnar cells with secretory granules
Relation of pulmonary artery to bronchus at each lung?
RALS– right anterior; Left superior
Structure that perforates diaphragm at T8, T10, and T10?
I ate ten eggs at twelve (IVC8; Esophagus10; Aorta12– also thoracic duct and azygos vein)
Inspiratory muscles during exercise?
External intercostals, Scalene, Sternocleidomastoid
Expiratory muscles?
Rectur abdonimin, internal and external obliques; transversus abdominis, internal intercostals
Physiologic dead space equations? (ventilation but no perfusion)
Vd= Vt X ((PaCO2- PECO2)/PaCO2) Taco, Paco, Peco Paco
Cyanide poisoning treatment? and MOA?
Nitrites to oxidize Hb to methemoglobin
Treatment of methemoglobin?
Methylene blue– treat met with methylene blue
What should be used to get rid of cyanide methemoglobin complex?
thisulfate– forms thiocyanate and is renally excreted
Cherry red blood?
Carbon monoxide poisoning
How does carbon monoxide effect the dissociation curve?
Shifts curve to left, but limits oxygen carrying capacity
Diffusion limited disorders?
CO, emphysema, fibrosis
Histology findings in pulmonary hypertension?
Plexiform lesions; intimal fibrosis and medial hypertrophy
Don’t forget about hypoxic vasoconstriction and its causes
Don’t forget about hypoxic vasoconstriction and its causes
Calculate A-a gradient
PAo2= PIo2- (paCO2/R)—
150-(PaCo2/R)
Oxygenation of Hb promotes dissociation of?
H+ from Hb; shifting equilibrium towards CO2 formation and CO2 release from RBCs
Patient presents with hypoxemia, delirium, and petechial rash. He broke his femus 2 days ago—?
Fat emboli– associated with bone fractures and liposuction
Remember petechial RASH