GI Drugs

Question 1

H2 potent inhibitor of cyp p450?

Answer 1

cimetidine

Question 2

H2 inhibitors that cause decrease in renal excretion of creatinine?

Answer 2

Cimetidine and ranitidine

Question 3

Proton pump inhibitors put people at increased risk for ?

Answer 3

C. difficile; hip fractures;and dec serum magnesium

Question 4

Binds to ulcer base?

Answer 4

Bismuth, sucralfate

Question 5

Big side effect of antacid use?

Answer 5

Hypokalemia due to metabolic alkalosis

Question 6

Can cause constipation and hypophosphatemia; proximal muscle weakness; seizures

Answer 6

Aluminum hydroxide

Question 7

Decreases the effectiveness of tetracycline via chelation?

Answer 7

calcium carbonate

Question 8

Sulfasalazine MOA?

Answer 8

combination of sulfapyridine (antibacterial) and 5ASA (antiinflammatory)

Question 9

Causes reversible oligospermia?

Answer 9

Sulfasalazine

Question 10

Used for postsurgery gastroparesis or diabetic gastroparesis? side effect?

Answer 10

Metoclopramide– can cause tarditive dyskinesia because it is a D2 receptor antagonist