Pathognomonic Flashcards

1
Q

Auspitz sign

A

Psoriasis (pinpoint bleeding spots from exposure of dermal papillae when scales are scraped off)

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2
Q

heliotrope rash

A

dermatomyositis

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3
Q

anti jo 1

A

dermatomyositis and polymyositis

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4
Q

Anti dna topoisomerase

A

Diffuse scleroderma

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5
Q

Anti centromere

A

CREST

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6
Q

anti citrullinated

A

Rheumatoid arthritis (citRUllinated)

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7
Q

Schaumann and asteroid bodies

A

Sarcoid (Asteroid has sarcoid)

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8
Q

Non caseating granuloma+ increased ACE

A

sarcoid

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9
Q

Anti smooth muscle

A

autoimmune hepatitis

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10
Q

Antihistone

A

Drug induced lupus

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11
Q

dactylitis

A

psoriatic arthritis

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12
Q

Assoc with temporal arteritis

A

polymyalgia rheumatica

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13
Q

Monosodium urate crystals

A

gout

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14
Q

calcium pyorphosphate crystals

A

pseudogout

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15
Q

Tophus

A

gout

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16
Q

Anti Ro

A

Sjogrens (also anti La) ribonucleoprotein

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17
Q

Anti La

A

Sjogrens (also anti Ro) ribonucleoprotein

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18
Q

Pannus

A

RA

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19
Q

HLA DR4

A

RA

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20
Q

Double bubble

A

Duodenal atresia or giant cell tumor of bone (epiphysis)

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21
Q

Blue cell tumor

A

Ewings sarcoma

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22
Q

Onion skin appearance in bone

A

Ewings sarcoma (also PSC and Tay sachs)

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23
Q

Glistening mass in medullary cavity

A

chondrosarcoma

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24
Q

Polyostotic fibrous dysplasia

A

(bone is replaced by fibroblast) think McCune Albright

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25
Q

Verrucae

A

warts– caused by hpv

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26
Q

Plaques with silvery scaling

A

Psoriasis

27
Q

Multiple seborrheic keratoses (stuck on)

A

Indicates underyling malignancy

28
Q

Honey colored crusting

A

impetigo

29
Q

IgG AB against demoglein 3

A

pemphigus vulgaris

30
Q

IgG agst hemidesmisomes

A

bullous pemphigoid (antibodies are bullow the epidermis)

31
Q

christmas tree distribution rash

A

Pityriasis Rosea

32
Q

Colles fracture

A

Osteoporosis (can happen otherwise but very common in osteoporosis)

33
Q

Chalk stick fracture

A

Pagets disease

34
Q

Mosaic bone pattern

A

Pagets

35
Q

Sun burst appearance on xray

A

Osteosarcoma

36
Q

Pleimorphic cells that produce osteoid

A

Osteosarcoma

37
Q

Soap bubble appearance on x ray

A

Giant cell tumor of bone (epiphysis; knee region)

38
Q

Polished ivory appearance of bone

A

Osteoarthritis

39
Q

Bamboo spine

A

Ankylosing spondylitis

40
Q

Wichams striae

A

Lichen planus (reticular white lines on surface)

41
Q

Postauricular lymphadenopathy

A

Rubella (when speaking about child with rash)

42
Q

Cherry red appearance of skin?

A

CO poisoining

43
Q

String of pearls?

A

Polyarteritis nodosa; PCOS; small bowel obstruction

44
Q

Strawberry cervix?

A

Trichimonas

45
Q

Strawberry tongue?

A

Kawasaki, Toxic Shock Syndrome, Scarlet Fever

46
Q

p anca?

A

Microscopic polyangitis (no granulomas); Churg Strauss; ulcerative colitis

47
Q

Vasculitis with IgA deposition?

A

Henoch Shonlein Purpura

48
Q

Targetoid rash?

A

Erythema multiforme or Lyme disease

49
Q

Charcot leyden crystals?

A

Asthma– eosinophilic breakdown in sputum

50
Q

Honey comb lung on xray?

A

Interstitial fibrosis

51
Q

Egg shell calcification?

A

Silicosis

52
Q

Ivory white calcified pleural plaque?

A

Asbestosis

53
Q

Chocolate agar blood and cyanosis?

A

Methemoglobin

54
Q

Golden brown fusiform rods–dumbbell shaped

A

Asbestos bodies (iron deposits)

55
Q

Hemosiderin laden macrophages?

A

Heart failure cells–macrophages consume blood–>build up of iron

56
Q

Nutmeg liver?

A

RHF

57
Q

Fixed splitting

A

ASD

58
Q

Boot shaped heart on xray?

A

TOF

59
Q

Hurthle cells

A

Hashimotos (also see lymphocytic infilitrates with germinal centers)

60
Q

Pretibial myxedema?

A

Hyperthyroidism

61
Q

Antimicrosomal antibody?

A

Hashimotos (also see antithyroglobulin)

62
Q

Antithyroglobulin antibody?

A

Hashimotos

63
Q

Dense core bodies

A

Carcinoid tumor

64
Q

Regenerative nodules and bridging fibrosis?

A

Cirrhosis