Mechanism of resistance antimicrobials

Question 1

Drug inactivated by acetylation phosphorylation, or adenylation?

Answer 1

Aminoglycosides

Question 2

Tetracycline MOR

Answer 2

dec uptake into cells or increased efflux out of cell

Question 3

Methylation of 23s rRNA binding site?

Answer 3

Macrolides

Question 4

Plasmid encoded acetyltransferase that inactivates drug?

Answer 4

Chloramphenicol

Question 5

MOR or fluoroquinolones?

Answer 5

Chromosome encoded mutations in DNA gyrase, plasmid mediated resistance, efflux pumps