Respiratory 2 Flashcards

1
Q

What are fluids

A

Substance that continually deforms (flows) under an applied shear stress (gas,liquid)

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2
Q

What is normal sea level atmospheric pressure but what do respiratory physiologist set atmospheric pressure to

A

760 mmHg
Set to 0 cm H2O or mmHg

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3
Q

What is atmospheric air

A

Mixture of gases

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4
Q

Dalton’s law

A

Total pressure exerted by a mixture of gases is the sum of the pressure exerted by each gas
- Determines atmospheric pressure

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5
Q

What Dalton’s law dependent on

A

Humidity of air

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6
Q

Pressure exerted by one gas is known as

A

Partial pressure
PO2 PCO2

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7
Q

Partial pressure of gas=

A

Patm x % of gas in atmosphere

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8
Q

Partial pressure of gas in humid air=

A

(Patm - PH2O) x % of gas

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9
Q

What is bulk flow

A

Composition of gases moving

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10
Q

How does gas move in respiratory system

A

Down pressure gradients
From region of high pressure to low

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11
Q

What is flow directly inverse to

A

Resistance

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12
Q

What is flow directly proportional to

A

The pressure difference between alveolar pressure and atmospheric pressure

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13
Q

What are relevant pressure related to flow

A

Alveolar pressure: Palv (at end)
Atmospheric pressure: Patm (set to 0, at start right outside mouth)

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14
Q

During inspiration what decreases

A

Alveolar pressure to create gradient to move air in

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15
Q

During expiration what increases

A

Alveolar pressure increases to create gradient to move air out

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16
Q

Palv>Patm

A

Expiration

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17
Q

Palv<Patm

A

Inspiration

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18
Q

What does boyle’s law describe

A

Pressure-volume relationships
Change in lung volume results in a change in lung pressure driving bulk flow of air

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19
Q

What is boyle’s law equation

A

(P1V1=P2V2)

20
Q

What happens to the pressure when the volume decreases to 0.5L?

A

P1V1=P2V2
100 mmHg x 1L = P2 x 0.5 L
200 mmHg =P2
Increased by 2

21
Q

What happens during inspiration

A

Make volume of our alveoli larger resulting in drop in pressure below atm pressure resulting in air flow from atmosphere to alveoli

22
Q

What is ventilation

A

Bulk flow exchange of air between the atmosphere and alveoli

23
Q

What is a single respiratory cycle (one complete ventilation)?

A

Single inspiration followed by an expiration

24
Q

What does spirometer measure

A

Lung volumes change

25
Tidal volume (TV)
Amount of air that enters or exits the lungs during quiet respiration (resting)
26
Tidal volume and frequency of breaths is
Total ventilation during rest
27
Total pulmonary ventilation
TV x frequency of breaths Amount of air moving in than out
28
Inspiration reserve volume
Additional air that could still be inspired after quiet inspiration
29
Expiratory reserve volume
After end of quiet expiration, the volume of air that still remains within the lungs that can be expired
30
Residual volume
Air remaining in lungs even after maximal expiratory effort (cannot be measured with spirometer)
31
What are the four primary volumes that do not overlap and are the total lung capacity
Tidal volume, inspiratory reserve volume, expiratory reserve volume, residual volume
32
What are the two important functions of the air left
1. Prevents airway collapse (small airways), after a collapse it takes large pressure to re-inflate 2. It allows continuous exchange of gases
33
Total lung capacity
Sum of all 4 volumes
34
Functional residual capacity
Capacity of air remaining in the lungs after quiet expirations, the sum of ERV and RV
35
Inspiratory capacity
Sum of IRV and TV representing the max amount of air that one can inspire after quiet expiration
36
Vital capacity
Sum of IRV, TV, and ERV representing the max achievable air moved with a single breath (everything but residual volume)
37
What is a pulmonary function test
Testing individuals forced vital capacity (FVC) and comparing to Force expired volume in one second (FEV1)
38
What is low initial FVC indicative of
Restrictive pulmonary disease (decrease in lung compliance) -COPD
39
What is FEV1 normally
~80% of vital capacity
40
What is below 80% of FEV1 indicative of
Obstructive pulmonary disease (increased resistance) - asthma
41
How do we change alveolar pressure
Inspiratory muscle (skeletal) to increase the volume of alveoli, resulting in decrease in pressure
42
What is 60-75% of inspiratory volume change due to
Diaphragm (base of thoracic cavity) Contracts and flattens
43
When is diaphragm relaxed
At end of expiration
44
What is the last 25-40% of inspiratory volume due to
Movements of rib cage
45
What muscles cause pump handle movement of sternum
External intercostals of upper ribs and scalenes - move sternum outward
46
What muscles cause bucket handle motion of ribs
External intercostals in lower ribs - lift ribs outward