Renal 1 Flashcards

1
Q

What urine characteristics have been used as indicators of health of body

A

Color, clarity, odor taste

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2
Q

What is the honey-urine disease

A

Diabetes

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3
Q

What is the most important function of the kidneys

A

Homeostatic regulation of water and ion content of the blood (salt-water balance or fluid-electrolyte balance)

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4
Q

6 other functions of kidneys

A
  1. Regulation of extracellular fluid volume and blood pressure
  2. Regulation of osmolarity
  3. Maintenance of ion balance
  4. Homeostatic regulation of pH
  5. Excretion of wastes
  6. Production of hormones
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5
Q

What ions are balanced by kidneys

A

Na, K, Ca

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6
Q

What wastes are excreted

A

Metabolic and xenobiotics (substances foreign to body)

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7
Q

How much kidney is need for function without disrupting homeostatsis

A

Can loose 3/4 kidney function

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8
Q

Where are kidneys located

A

Retro-peritoneally wedged against back muscles

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9
Q

How much of cardiac output does urinary system recieve

A

20-25%

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10
Q

Cortex

A

Outer lighter region

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11
Q

Medulla

A

Triangle inner portion

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12
Q

Renal pelvis

A

Vasculature and nerves and ureter

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13
Q

Where are nephrons

A

Inside renal pyramids

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14
Q

What are nephrons

A

Functional unit of kidneys

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15
Q

2 kinds of nephrons

A

80% cortical nephrons (most in cortex)
20% juxtamedullary nephrons (junction between cortex and medulla and extend down into medulla)

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16
Q

What parts of nephron does cortex contain

A

Bowman’s capsules, proximal and distal tubules

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17
Q

What part of nephron does medulla contain

A

Loops of henle and collecting ducts

18
Q

What is the order of the renal vascular components

A

L+R renal arteries- afferent arterioles - glomerulus (capillaries) - efferent arterioles - peritubular capillaries - L+R renal vein

19
Q

On the juxtamedullary nephron what is the peritubular capillaries called when they extend in medulla

A

Vasa recta

20
Q

The renal system is a portal system. What is a portal system

A

2 linked capillary beds exist and interact

21
Q

Where does filtration occur

A

Glomerulus into bowman’s capsule

22
Q

Where does reabsorption and secretion occur

A

Peritubular capillaries

23
Q

What is the order of the tubular component of the nephron

A

Bowman’s capsule - proximal tubule - descending loop of henle - ascending loop of henle - distal tube - collecting duct

24
Q

What is the nephron made up of

A

Single layer of epithelial cells

25
What 4 processes do the kidneys complete
Filter, reabsorb, secrete, excrete
26
Filtration
Bulk flow of fluid and dissolved solutes from the glomerulus (blood) to bowman’s capsule (lumen)
27
Secretion
From blood into lumen of nephron
28
Reabsorption
From lumen of nephron to blood
29
Why is reabsorption important
Some substances from bulk flow we want back in body
30
Excretion
From lumen to outside of body
31
Where is only place you see filtration
Glomerular capillary
32
What 3 processes happen in nephron
1. Glomerular filtration 2. Tubular secretion 3. Tubular reabsorption
33
How much plasma is filtered at the glomeruli each day? How much is reabsorbed? How much excreted?
180L >99% is reabsorbed ~1.5L/day is excreted
34
What is filtrate? What is urine?
Fluid enters bowman’s capsule Urine exits collecting duct
35
How much reabsorption occurs in proximal tubule
~70%
36
What kind of reabsorption happens at descending and ascending loops of henle
Descending= fluid Ascending= solute
37
What is the loop of henle responsible for
Creating dilute urine (hyposmotic - solute absorbed exceeds water)
38
What does the distal tubule and collecting duct regulate
Salt and water balance under the control of hormones
39
What varied for the urine excreted
The final volume and osmolarity - based on what we need - if dehydrated reabsorb water, osmolarity increases
40
What do not all substances undergo in plasma
Filtration and/or secretion and/or reabsorption
41
How to fin the amount excreted
Amount filtered - amount reabsorbed + amount secreted = amount excreted