Repro 1 Flashcards

1
Q

Role of reproduction

A

Making new humans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Why are we advanced when it comes to reproduction

A
  1. Mate for pleasure and procreation
  2. Does not only occur during “fertile” periods
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Sexually dimorphic

A

Males and females have distinct physical characteristics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Male and female sex organs consist of 3 sets of structure

A

Gonad, internal genitalia, external genitalia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Gonads

A

Gamete producing organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Internal genitalia

A

Accessory glands and ducts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

External genitalia

A

External reproductive structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where is sex determined

A

Programmed in genome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Each nucleated cell of body except gametes contains

A

23 pairs of chromosomes (46 total: diploid)
22 pairs autosomes: direct development of human body
1 pair sex chromosomes: direct development of internal and external sex organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What do gametes contain

A

23 single chromosomes (haploid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Each egg produced by a female has

A

An X chromosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Sperm produced by male has either

A

And X chromosome or a Y

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In females during early embryonic development what happens to one X chromosome

A

Turns off in each cell
- whether paternal or maternal X is shut off differs in each cel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What x-linked genetic disorders more commonly affect males

A

Muscular dystrophy, color blindness, hemophilia
(Expressed because they only have one X)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

If there’s a Y chromosome

A

Genetically male

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are 2 ways there can be abnormal sex chromosome distribution

A

Non disjunction at meiosis 1
- both go into 1 secondary gamete
- one pair of disomic gametes and one pair of nullisomic
Non disjunction at meiosis 2
- one disomic(2 chromatids one gamete) and one nullisomic gamete in a pair
- one pair normal monosomic gametes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

XXY

A

Klinefelters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

X

A

Turner syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Y

A

Non viable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Stages of egg

A

Egg-zygote-2 cell stage- 4 cell stage - morula- blastocyst

21
Q

Embryonic period extends through

A

The 8th week

22
Q

What is the time of a standard pregnancy

A

38 weeks development
40 weeks because standard pregnancy is measured from first day of last mentrual cycle

23
Q

When is fetus

24
Q

Wet do reproductive structures begin to differentiate

A

Seventh week of development

25
Prior to time of reproductive differentiation considered
Bipotential Has capacity to become male or female
26
When bipotential, gonads are
Outer cortex and innner medulla
27
What are the 2 accessory ducts when bipotential
Wolffian and Müllerian duct
28
In female gonad cortex
Forms ovary
29
If female gonad medulla
Regresses
30
If female wolffian duct
Regressses (testosterone absent)
31
If female Müllerian duct
Becomes fallopian tube, uterus, cervix, and upper 1/2 vagina (AMH absent)
32
If male gonad cortex
Regresses
33
if male Gand medulla
Forms testis
34
If male wolffian duct
Forms epidiidymis, vas deferents, and seminal vesicle (testosterone present)
35
If male Müllerian duct
Regresses (AMH present- testis produces)
36
Male or female development depends on the presence or absence of
Sex determining region of the Y chromosome (SRY gene)
37
SRY gene
Guides development of internal genitalia into male and inhibit female internal
38
What does SRY produce
Testis determining factor (TDF) - SOX9, WT1, SF1
39
What does TDF do
Guide development of gonadal medulla into testis
40
What hormones does the testes then produce
Anti-mullerian hormone Testosterone Di hydro testosterone
41
Anti mullerian hormone
Sertoli cells Causes Müllerian ducts to regress
42
Testosterone
Leydig cells Converts wolffian ducts into male acccesory structures
43
Dihydrotestosterone
Leydig cells Differentiation of external genitalia
44
Interstitial cells or Leydig cells secrete
Testosterone
45
Sertoli cells secrete
Anti-mullerian hormone
46
At 10 weeks of female growth
Gonadal cortex becomes ovary in absence of SRY protein and influence of female genes Absence of testosterone causes wolffian duct to degenerate
47
At birth what happens to females
Absence of AMH allows Müllerian duct to become fallopian tube, uterus, and upper part of vagina
48
At 10 weeks of male growth
SRY protein directs medulla of bipotential gonad to develop into testis AMH from testis causes Müllerian ducts to disppear
49
At birth for males
Testosterone from testis converts wolffian duct into seminal vesicle, vas deferents, epidydimis DHT controls prostate development