RESP SYSTEM - ANAPHYLAXIS, ALLERGIES, CROUP + CF Flashcards

1
Q

What do 1st generation antihistamines do compared to 2nd generation?

A

More sedating

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2
Q

What 2 1st generation antihistamines are more sedating than chlorphenamine?

A

alimemazine + promethazine

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3
Q

List some 1st gen antihistamines?

A

Chlorphenamine

Cyclizine

Alimemezine*

Promethazine*

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4
Q

List 5 2nd gen antihistamines

A

Acrivastine

cetirizine

desloratadine

loratadine

fexofenadine (OTC now)

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5
Q

What antihistamines can be used for N + V?

A

Cyclizine

promethazine

cinnarizine

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6
Q

What antihistamine is used for migraines?

A

Buclizine (migraleve)

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7
Q

What is immunotherapy?

A

Allergen vaccine - reduces asthma + allergic symptoms

can contain dust mites, animal dander + pollen extract

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8
Q

Vaccines contains what extract can reduce risk of severe anaphylaxis?

A

Bee or wasp venom

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9
Q

What is a SE of omalizumab?

A

Hypersensitivity

Churg Strauss syndrome

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10
Q

What is anaphylaxis?

A

Severe life threatening hypersensitivity reaction

Caused by allergens

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11
Q

What is anapgylaxis management?

A
  1. Auto injector ASAP - adrenaline
  2. 999 + say anaphylaxis - CPR if needed.
  3. Lie down + raise patients legs
  4. remove triggers
  5. repeat after 5 min interval if no improvement
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12
Q

what is given after anaphylaxis resolved?

A

Oxygen

IV fluids - if shock

Non-sedating oral antihistamine- when stable

Inhaled bronchodilator therapy e.g salbutamol if needed

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13
Q

What is adrenaline doses for child up to 6 months of age?

A

100-150mcg

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14
Q

What is adrenaline doses for child 6 months - 5 yrs?

A

150mcg

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15
Q

What is adrenaline doses for child 6 - 11 yrs?

A

300 mcg

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16
Q

What is adrenaline doses for over 12 yrs?

A

500mcg

17
Q

How many auto injectors should be prescribed ?

A

2

18
Q

What is mild croup treatment?

A

single dexamethasone oral dose

19
Q

What is severe croup treatment?

A

Hospital admission

Single dose pred or dexamethasone orally

If not able to take oral = IM dex or nebulised budesonide

20
Q

What to do if cannot take oral steroid for severe croup?

A

IM dex or nebulised budesonide

21
Q

What to give if severe croup not solved by steroids?

A

Nebulised adrenaline

22
Q

What is cystic fibrosis?

A

genetic disorder affecting lungs, pancreas, liver, intestine + reproductive organs

causes viscus sputum, chest infections + malabsorption

23
Q

What is treatment for CF?

A

Mucolytics e.g. dornase alfa

causes clearance of sputum.

Antibacterials
Pancreatin

24
Q

What 3 things to monitor for CF patients?

A

Liver disease

diabetes

bone density