RESP SYSTEM - ANAPHYLAXIS, ALLERGIES, CROUP + CF Flashcards
What do 1st generation antihistamines do compared to 2nd generation?
More sedating
What 2 1st generation antihistamines are more sedating than chlorphenamine?
alimemazine + promethazine
List some 1st gen antihistamines?
Chlorphenamine
Cyclizine
Alimemezine*
Promethazine*
List 5 2nd gen antihistamines
Acrivastine
cetirizine
desloratadine
loratadine
fexofenadine (OTC now)
What antihistamines can be used for N + V?
Cyclizine
promethazine
cinnarizine
What antihistamine is used for migraines?
Buclizine (migraleve)
What is immunotherapy?
Allergen vaccine - reduces asthma + allergic symptoms
can contain dust mites, animal dander + pollen extract
Vaccines contains what extract can reduce risk of severe anaphylaxis?
Bee or wasp venom
What is a SE of omalizumab?
Hypersensitivity
Churg Strauss syndrome
What is anaphylaxis?
Severe life threatening hypersensitivity reaction
Caused by allergens
What is anapgylaxis management?
- Auto injector ASAP - adrenaline
- 999 + say anaphylaxis - CPR if needed.
- Lie down + raise patients legs
- remove triggers
- repeat after 5 min interval if no improvement
what is given after anaphylaxis resolved?
Oxygen
IV fluids - if shock
Non-sedating oral antihistamine- when stable
Inhaled bronchodilator therapy e.g salbutamol if needed
What is adrenaline doses for child up to 6 months of age?
100-150mcg
What is adrenaline doses for child 6 months - 5 yrs?
150mcg
What is adrenaline doses for child 6 - 11 yrs?
300 mcg