FUNGAL INFECTIONS Flashcards

1
Q

What is tx for aspergillosis?

A

Voriconazole

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2
Q

What is cryptococcosis?

A

Amphotericin B

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3
Q

What is tx for vaginal thrush?

A

Clotrimazole or fluconazole

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4
Q

What is tx for oral thrush?

A

Nystatin

Miconazole

fluconazole

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5
Q

What is nail fungal infection tx?

A

Topical -

If not systemic - terbinafine or itraconazole

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6
Q

When to refer if nail fungal infection?

A

If under 18

diabetes

pregnant/ breastfeeding

More than 2 nails infected

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7
Q

2 main SEs of anti-fungals?

A

QT prolongation

hepatotoxic

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8
Q

What improves itraconazole bioavailability?

A

Fizzy drinks

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9
Q

What antifungal is lower risk of QT prolongation + hepatotoxicity?

A

Fluconazole

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10
Q

What anti-fungal has life threatening hepatotoxicity?

A

Ketokonazole - oral tx suspended

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11
Q

What reaction occurs with voriconazole use?

A

phototoxicity

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12
Q

What organ failure can amphotericin B cause?

A

Renal failure

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13
Q

Risk of —— in IV amphotericin B ?

A

Anaphylaxis - TEST dose within 3p0 mins

maintain same formulation

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