FUNGAL INFECTIONS Flashcards
What is tx for aspergillosis?
Voriconazole
What is cryptococcosis?
Amphotericin B
What is tx for vaginal thrush?
Clotrimazole or fluconazole
What is tx for oral thrush?
Nystatin
Miconazole
fluconazole
What is nail fungal infection tx?
Topical -
If not systemic - terbinafine or itraconazole
When to refer if nail fungal infection?
If under 18
diabetes
pregnant/ breastfeeding
More than 2 nails infected
2 main SEs of anti-fungals?
QT prolongation
hepatotoxic
What improves itraconazole bioavailability?
Fizzy drinks
What antifungal is lower risk of QT prolongation + hepatotoxicity?
Fluconazole
What anti-fungal has life threatening hepatotoxicity?
Ketokonazole - oral tx suspended
What reaction occurs with voriconazole use?
phototoxicity
What organ failure can amphotericin B cause?
Renal failure
Risk of —— in IV amphotericin B ?
Anaphylaxis - TEST dose within 3p0 mins
maintain same formulation