NERVOUS SYSTEM - ANXIETY Flashcards
What is anxiety?
Normal emotion, can be severe, disabling + chronic
What are 5 symptoms of anxiety?
Worry
Fear
Restlessness
Irritability
Difficulty concentrating
List 6 physical symptoms?
Palpitations
Tremors
Muscle tension
Sweating
SOB
Insomnia
What are the 2 main classes of anxiolytic drugs?
Benzodiazepines
Beta blocker
What are 2 drugs used for chronic anxiety?
SSRI
Propranolol - physical symptoms
List 4 short acting benzodiazepines?
Triazolam
Midazolam
Oxazepam
Lorazepam
What 3 benzodiazepines are also used in insomnia treatment?
Diazepam
Oxazepam
Lorazepam
What are 5 long acting benzodiazepines?
Chlordiazepoxide
Diazepam
Clorazepate
Flurazepam
Clobazam
What is the risk of long acting benzos in elderly patients?
Can induce hepatic coma
What type of benzos is best used in elderly patients?
Short acting benzos
e.g. lorazepam, oxazepam, midazolam
What schedule drug is benzodiazepines?
Sch 4 part 1
What 4 drug classes can be used to treat anxiety?
5HT1a alpha = buspirone
Antidepressant
Anti-epileptic
Anti-psychotic
What is MOA of benzodiazepines?
Increasing binding of GABA at GABAa receptors.
Causes CNS depressant effects
What is clobazam used in also?
Epilepsy
What is chlordiazepoxide used for?
Acute alcohol withdrawal
What 2 benzodiazepines can be used in dental procedures?
Temazepam **
Diazepam
Which 5-ht1A agonist is used for anxiety and does NOT cause dependancy?
Buspirone