NERVOUS SYSTEM- MULTIPLE SCLEROSIS Flashcards
What is MS?
Chronic autoimmune disease demyelinating CNS system
What 3 types is MS split into?
Relapsing
Progressive
Both
What does active MS mean?
2 relapses in past 2 years even with treatment with interferon beta
What is aim of MS management?
Symptom relief
What are the 5 symptoms MS patients get?
Spasticity
relapses
Oscillopsia
Mood alterations
Fatigue
What 4 drugs can be given for Spasticity?
Baclofen
diazepam
Dantrolene
tizanidine
What drug is given for MS relapses?
Methylprednisolone
What is oscillopsia?
objects seem to vibrate
oscillopsia drug treatment?
Gabapentin
What drug is given for mood alteration?
amitriptyline
What 2 drugs are given for fatigue?
Fampridine
Amantadine
Why is baclofen dose increased SLOWLY?
To reduce major side effects of sedation + hypotonia.
Why is it important NOT to stop baclofen randomly?
Avoid abrupt withdrawal- can increase spasticity, autonomic dysfunction-e.g. hyperthermia, convulsions.
