resp onc 7

Question 1

G1 phase

Answer 1

postmitotic phase … RNA used in DNA synthesis is made here

Question 2

G2 phase

Answer 2

premitotic phase … marked by RNA and protein synth… double check repair

Question 3

where are ependymomas most commonly found

Answer 3

4th ventricle … can cause hydrocephalus

Question 4

7 year old girl…. cold intolerance, short stature, polyuria ……supratentorial mass

Answer 4

craniopharyngioma … rakthe puch remnants

Question 5

neucleotide excision repair defect

Answer 5

XP …. rmmber 20% of these pts can also present with neurological defects like unsteady gait

Question 6

non homologous end joining

Answer 6

ataxia telengectasia

Question 7

aspiration pneumonia lung abscess bacteria and txt

Answer 7

mostly mixed or facultative anaerobic bacteria

txt … ampicillin/sulbactam or amoxcillin/clavulinc acid

Question 8

pulmonary embolism txt

Answer 8

heparin only thrombolytics if hemodynamically unstable

Question 9

type 2 pneumocytes other function that making surfactant

Answer 9

prolif during liung damage

Question 10

what is special about TB in pt withs HIV

Answer 10

PPD can be negative too

Question 11

periodic acid schiff stain

Answer 11

whipplei

Question 12

good pasture

Answer 12

not assoc with c anca ….

Question 13

hemoptysis dyspnea weight losss postiive c anca

Answer 13

granulomatosis with polyangitis

Question 14

turcot syndrome

Answer 14

AD colorectal and brain tumors

Question 15

Turcot has two diff mutations what are they

Answer 15

APC … medulloblastoma

MLH1 …DNA mismatch repair gene …. glioblastoma multiforme

Question 16

Gardner syndrome

Answer 16

osteomas, bone and soft tissue tumors, congenital hypertrophy of retinal pigment epithelium and dental abnormalities

Question 17

several extracellular, calcified, spherical bodies…. thyroid tumor

Answer 17

psamoma bodies … finely dispersed chromatin plus optically clear nuclei orphan ann eyes

Question 18

acellular amyloid deposits … thyroid cancer calcitonin producing

Answer 18

medullary

Question 19

uniform follicles containing colloid

Answer 19

follicular

Question 20

monoclonal igM gammapathy

Answer 20

waldenstrom … may cause blussed vision or raynauds

Question 21

myelosupp and pancytopenia caused by methotrexate treat by

Answer 21

folic acid

Question 22

bleomycin vs buslfan

Answer 22

both cause p fibrosis but busulfan takes longer

Question 23

pulmonary hypoplasia caused by

Answer 23

oligohydramnios, premature rupture of membranes, congenital hernia pleural effusion

Question 24

what can cause preterm birth polyhydramnios or olygohydramnios

Answer 24

POLY

Question 25

causes of polyhydramnios

Answer 25

increase production or decrease absp 
tracheoesophageal fistula 
duodenal  atresia
anencephaly
material diabetes