resp onc 7 Flashcards

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1
Q

G1 phase

A

postmitotic phase … RNA used in DNA synthesis is made here

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2
Q

G2 phase

A

premitotic phase … marked by RNA and protein synth… double check repair

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3
Q

where are ependymomas most commonly found

A

4th ventricle … can cause hydrocephalus

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4
Q

7 year old girl…. cold intolerance, short stature, polyuria ……supratentorial mass

A

craniopharyngioma … rakthe puch remnants

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5
Q

neucleotide excision repair defect

A

XP …. rmmber 20% of these pts can also present with neurological defects like unsteady gait

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6
Q

non homologous end joining

A

ataxia telengectasia

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7
Q

aspiration pneumonia lung abscess bacteria and txt

A

mostly mixed or facultative anaerobic bacteria

txt … ampicillin/sulbactam or amoxcillin/clavulinc acid

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8
Q

pulmonary embolism txt

A

heparin only thrombolytics if hemodynamically unstable

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9
Q

type 2 pneumocytes other function that making surfactant

A

prolif during liung damage

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10
Q

what is special about TB in pt withs HIV

A

PPD can be negative too

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11
Q

periodic acid schiff stain

A

whipplei

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12
Q

good pasture

A

not assoc with c anca ….

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13
Q

hemoptysis dyspnea weight losss postiive c anca

A

granulomatosis with polyangitis

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14
Q

turcot syndrome

A

AD colorectal and brain tumors

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15
Q

Turcot has two diff mutations what are they

A

APC … medulloblastoma

MLH1 …DNA mismatch repair gene …. glioblastoma multiforme

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16
Q

Gardner syndrome

A

osteomas, bone and soft tissue tumors, congenital hypertrophy of retinal pigment epithelium and dental abnormalities

17
Q

several extracellular, calcified, spherical bodies…. thyroid tumor

A

psamoma bodies … finely dispersed chromatin plus optically clear nuclei orphan ann eyes

18
Q

acellular amyloid deposits … thyroid cancer calcitonin producing

A

medullary

19
Q

uniform follicles containing colloid

A

follicular

20
Q

monoclonal igM gammapathy

A

waldenstrom … may cause blussed vision or raynauds

21
Q

myelosupp and pancytopenia caused by methotrexate treat by

A

folic acid

22
Q

bleomycin vs buslfan

A

both cause p fibrosis but busulfan takes longer

23
Q

pulmonary hypoplasia caused by

A

oligohydramnios, premature rupture of membranes, congenital hernia pleural effusion

24
Q

what can cause preterm birth polyhydramnios or olygohydramnios

A

POLY

25
Q

causes of polyhydramnios

A
increase production or decrease absp 
tracheoesophageal fistula 
duodenal  atresia
anencephaly
material diabetes