Resolutions Flashcards
1
Q
Catalytic kinetic resolutions
A
start with racemic mixture of enantiomers, place in chiral environment, one enantiomer reacts quicker
2
Q
Jacobsen kinetic resolution of epoxides
A
alkene and mCPBA gives mixture of epoxides, using chiral Co(III) helps distinguish them
3
Q
Reaction conditions for jacobsen if we want epoxide
A
slight excess of water, all of dashed reacted away, wedged converts and happens again
4
Q
reaction conditions for jacobsens if we want diol
A
slightly less water, lose a bit of dashed as not enough water to ring open it all
5
Q
dynamic resolutions
A
involves interconverting pairs of enantiomers
6
Q
dynamic kinetic
A
one of interconverting pair reacts faster
7
Q
thermo dynamic resolution
A
one of the interconverting pairs is more stable
