Oxidation Flashcards
1
Q
SeO2
A
selectively oxidises allylic, benzylic or a-to CO
2
Q
Jones
A
CrO3, H2SO4 and acetone
secondary alcohol to ketones
primary alcohol to carboxylic acids
3
Q
PDC
A
pyridinium dichromate
secondary alcohol to ketones
primary alcohol to aldehydes
milder, can be done in organic solvents
4
Q
TPAP
A
tetra-n-propylammonium perruthenate
alcohols to aldehydes/ketones
mild
catalytic using stoichiometric co-oxidant NMO
needs molecular sieves to remove water from reaction
5
Q
Dess-martin periodinane
A
alcohols to aldehydes/ketones
mild, good functional group tolerance
expensive and shock sensitive
6
Q
Swern
A
(COCl)2, DMSO at -78C then Et3N
alcohols to aldehydes/ketones
mild but smelly
