Reproductive hormones Flashcards
What is ganirelix and what is it used for?
It is a GnRH antagonist, preventing initial flare of FSH and LH, used to suppress levels for ovulation control.
It can also be used as an antiandrogen therapy for prostate cancer.
What is a GnRH agonist and what is it used for?
Leuprorelin can be used to treat prostate cancer, endemetrosis, and precocious puberty
What is follitropin used for?
Infertility in women for proven hypopituitarism
Superovulation treatment used in assisted conception
What two drugs are used in oral contraceptives?
Ethinyl estradiol and norethisterone
Name 3 SERMs and their function
Tamoxifen - used for breast cancer but partial agonist to uterus
Raloxifen - used for osteoporosis
Anastrazole - used for breast cancer as an aromatase inhibitors