Hyper and Hypothyroidism Flashcards
1
Q
How would you treat hypothyroidism?
A
Levothyroxine - synthetic T4 analogue
2
Q
How would you treat hyperthyroxine?
A
Propylthiouracil
Carbimazole
These are both thyroid peroxidase inhibitors that prevent the iodination of thyroglobin.
3
Q
Which drugs is more effective for quicker onset in hyperthyroidism?
A
PTU –> also prevents peripheral conversion of T4-T3 by selenodeiodinase.
4
Q
What is a side effect of PTU and carbimazole?
A
Agranulocytosis, pancytopenia, fever, headache, malaise
5
Q
What is a side effect of levothyroxine?
A
Angina and heart failure
6
Q
What are side effects of using iodine 131?
A
Worsening of thyroid eye disease
Hypothyroidism effects
