Artherosclerosis and lipid lowering drugs

Question 1

What are 6 different drug types used to treat artherosclerosis?

Answer 1

Simvastatins 
Ezetimibe 
Bile acid sequestrants 
Fibrates 
Lomitapide 
Niacin

Question 2

Name two statins

Answer 2

Simvastatin

Atorvastatin

Question 3

What are the function of statins

Answer 3

HMG Coreductase inhibitors of rate limiting step of cholesterol synthesis.

Question 4

Side effect of statins

Answer 4

Liver damage

Muscle inflammation

Question 5

What are the function of bile acid sequestrants?

Answer 5

Colestyramine and Colestipole

Question 6

What does ezetimibe do?

Answer 6

Prevent uptake of cholesterol and used as an adjunct

Question 7

What are some side effects of niacin?

Answer 7

GI side effects, flushing due to prostaglandin production

Question 8

What is lomitapide

Answer 8

Microsomal triaglyceride transfer protein inhibitor

Question 9

What is the function of phenofibrate and bezafibrate?

Answer 9

PPARalpha agnoists that decrease serum TAG, increase fatty acid oxidation