Hypertension

Question 1

How would you treat hypertension for below 55 and non afrocarribean?

Answer 1

1. ACE Inhibitor / ATII inhibitor / B-blocker

2. Diuretic thiazides, Ca2+ antagonist

Question 2

How would you treat hypertension for above 55 or afrocarribean?

Answer 2

1. Ca2+ antagonist, diuretic thiazide

2. ACE inhibitor/ ATII inhibitor/ B blocker

Question 3

Drug and function: minodixil

Answer 3

K+ activators to close L type calcium channels for weaker contraction and vasodilation. Given with B antagonist

Question 4

Drug and function: hydralazine

Answer 4

K+ activators to close L type calcium channels for weaker contraction and vasodilation. Given with B antagonist

Question 5

Side effect of captopril

Answer 5

Cough inducer, increase in renin, hyper kalamia, hypotension

Question 6

Side effect of losartan

Answer 6

Increase in renin, hyper kalamia, hypotension

Question 7

Side effect of bendroflumethiazide

Answer 7

Gout, impotence, Kidney stones, Hypercalcaemia, hypokalaemia, hyperglycaemia

Question 8

Side effect of verapimil

Answer 8

facial flushing, dizziness, headaches

Question 9

Side effect of amlodipine

Answer 9

facial flushing, dizziness, headaches

Question 10

Side effect of minodixil

Answer 10

Hyperglycaemia, reflex tachycardia, RAS activation, hypertrichosis

Question 11

What are contraindications of beta blockers?

Answer 11

Diabetics, aesthematics, peripheral vascular disease

Question 12

What are the functions of beta blockers?

Answer 12

Blocks sympathetic effects, slows heart rate and contraction, inhibits the RAS system.

Question 13

Side effects of prazosin

Answer 13

Reflex tachy cardia, postural hypotension,

Question 14

Function of a-methyl dopa

Answer 14

Prodrug acting on A2 receptors.

Question 15

Side effects of beta blockers?

Answer 15

Cold hands and feet, fatigue, bronchospasm, bradycardia

Question 16

What can be used for pre-eclampsia and what side effects does the drug have

Answer 16

Clonidine,

Dry moth, postural hypotension.