Repevant Exam Flash Cards Type 2 Diabetes

1
Q

What are the primary characteristics of Type 2 Diabetes (T2D)?

A

• Metabolic condition: Insulin resistance and impaired glucose regulation.
• Symptoms: Hyperglycemia, fatigue, excessive thirst, frequent urination.
• Complications: Cardiovascular disease, neuropathy, retinopathy, kidney disease.

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2
Q

Why is exercise important for managing Type 2 Diabetes?

A

Exercise helps improve insulin sensitivity, aids in weight management, and can lower blood sugar levels.

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3
Q

Why is exercise important for managing Type 2 Diabetes?

A

• Improves insulin sensitivity and glucose uptake in muscles.
• Reduces blood glucose levels and HbA1.
• Enhances cardiovascular fitness, reducing the risk of comorbidities.
• Supports weight management and improves lipid profiles.

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4
Q

What types of exercise are most effective for Type 2 Diabetes?

A
  1. Aerobic exercise: Walking, cycling, or swimming (30-60 minutes, 5 days per week).
  2. Resistance training: 2-3 days per week, targeting all major muscle groups.
  3. High-Intensity Interval Training (HIIT): Short bursts of high-intensity exercise improve glucose control.
  4. Flexibility and balance exercises: To reduce fall risk in older adults.
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5
Q

What is the first mechanism by which exercise benefits 2D?

A

Muscle glucose uptake: Exercise stimulates GLUT-4 translocation, increasing glucose transport into cells.

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6
Q

What is the second mechanism by which exercise benefits 2D?

A

Insulin sensitivity: Enhanced through reduced fat accumulation and improved mitochondrial function.

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7
Q

What is the third mechanism by which exercise benefits 2D?

A

Weight loss: Reduces adipose tissue, improving metabolic health.

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8
Q

What is the fourth mechanism by which exercise benefits 2D?

A

Anti-inflammatory effects: Lower levels of cytokines like IL-6 and CRP.

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9
Q

What are common barriers to exercise for people with 12D?

A

• Fear of hypoglycemia during or after exercise.
• Lack of knowledge about safe exercise practices.
• Limited access to exercise facilities or structured programs.
• Comorbid conditions like obesity, arthritis, or cardiovascular issues.

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10
Q

What are the anti-inflammatory effects related to cytokines?

A

Lower levels of cytokines like IL-6 and CRP.

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11
Q

What are key outcome measures used in 2D exercise studies?

A

• Glycemic control: Blood glucose, HbA1c.
• Insulin sensitivity: Measured by HOMA-IR or glucose tolerance tests.
• Body composition: BMI, waist circumference, or fat mass.
• Cardiorespiratory fitness: VO₂ max or step tests.
• Inflammation: Blood-based markers like IL-6, CRP.

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12
Q

What are the gaps in knowledge about exercise for 2D?

A

Lack of long-term studies examining exercise adherence and sustainability.

None

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13
Q

What is a limitation in research regarding exercise for specific populations?

A

Limited research on the optimal intensity and type of exercise for specific populations.

None

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14
Q

What is insufficiently studied regarding exercise’s effects?

A

Insufficient data on exercise’s effects on complications like neuropathy or retinopathy.

None

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15
Q

What is needed for better understanding in exercise science?

A

Need for better understanding of the role of HIIT in glycemic control.

None

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16
Q

How can adherence to exercise programs for T2P be improved?

A

Incorporate goal-setting and self-monitoring tools (e.g., pedometers, apps).
Provide education about the benefits and safety of exercise.
Include social support or group-based exercise programs.
Offer flexible, home-based, or community-centered interventions.

17
Q

What should be a cornerstone of 2D management?

A

Exercise should be a cornerstone of 2D management alongside diet and medication.

18
Q

What can structured exercise programs improve?

A

Structured programs can significantly improve glycemic control and reduce medication dependence.

19
Q

Why are tailored interventions important?

A

Tailored interventions are crucial for addressing individual barriers and needs.

20
Q

What is the importance of tailored interventions?

A

Tailored interventions are crucial for addressing individual barriers and needs.

21
Q

What limitations are common in T2D exercise studies?

A

Small sample sizes or homogeneous populations limit generalizability.

Short intervention durations may not reflect long-term outcomes. Over-reliance on self-reported data for physical activity adherence.