Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Flash Cards For Relevant Exam Rhematoid Arhritis > Exercise For Psychosis > Flashcards

Exercise For Psychosis Flashcards

1
Q

What are positive psychotic symptoms?

A

Hallucinations, Delusions, Disorganised Speech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are negative psychotic symptoms?

A

Anhedonia, Anergie, Apatry, Avolition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are cognitive symptoms of psychosis?

A

Cognitive Impairment, Poor Memory, Processing Speed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the global prevalence of schizophrenia?

A

Schizophrenia affects over 20 million individuals worldwide.

(1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where does schizophrenia rank in terms of debilitating disorders?

A

Schizophrenia is ranked within the top 10 of the most debilitating disorders in the Global Burden of Disease Review.

(2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the estimated economic burden of schizophrenia by 2026?

A

The economic burden of schizophrenia is estimated to amount to 23.7 billion by 2026.

(3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is psychosis?

A

An episode where one is detached from reality.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is schizophrenia?

A

A mental illness that impacts thought processes, emotions, and behavior.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What can cause psychosis?

A

It can be a symptom of sleep deprivation, substance use, mental illness, and other conditions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the criteria for diagnosing schizophrenia?

A

One must experience at least two of the following symptoms for six months, including one of the first three:

  1. Hallucinations
  2. Delusions
  3. Disorganized speech.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are signs of psychosis?

A

Signs include hallucinations, delusions, disorganized speech, and negative symptoms such as lessened emotional expression.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the incidence rate of first episode psychosis in England?

A

31.7 per 108,000

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is a crucial intervention point for first episode psychosis?

A

The first 5 years since symptom onset

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why is early intervention in psychosis important?

A

It is both clinically effective and cost-effective.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does early intervention limit?

A

Experiences with severe and debilitating symptom subtypes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the state of pathology in early intervention?

A

It is still in its infancy and can change the trajectory of illness.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the benefits of early intervention?

A

Better symptomatic and functional outcomes, improved psychological condition, and increased chances of optimum recovery.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the primary function of antipsychotic drugs?

A

Effectively reduce positive symptoms experienced in PEP/SeZ.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What positive symptoms do antipsychotic drugs target?

A

Hallucinations, delusions, anxiety.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which receptor do antipsychotic drugs operate via?

A

C2 dopamine receptor.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is regulated by antipsychotic drugs?

A

Dopaminergic transmission.

22
Q

What is a limitation of antipsychotic drugs?

A

They fail to ameliorate negative symptoms and cognitive deficits in 33% of schizophrenia cohorts.

This means that a significant portion of patients do not respond to these medications.

23
Q

What are some side effects of antipsychotic drugs?

A

They can induce further extrapyramidal symptoms, poor motivation, and emotional numbing.

24
Q

What are some health risks associated with antipsychotic drugs?

A

They are linked to cardiovascular disease and metabolic syndrome.

25
Q

What is the weight gain associated with Haloperidol?

A

Haloperidol can cause weight gain ranging from 7.4 to 9.2 kg (16.3 to 20.3 lbs).

26
Q

What is the primary focus of exercise as therapy?

A

Anti-inflammatory mechanisms.

27
Q

What percentage of maximum effort is associated with IL-6?

A

> 60% maximum.

28
Q

What physiological benefit does exercise provide?

A

Offsets AP induced weight gain.

29
Q

How does exercise impact metabolic and cardiovascular diseases?

A

Prevents metabolic syndrome and cardiovascular disease (insulin, glucagon).

30
Q

What risk does exercise reduce?

A

Reduces premature mortality risk.

31
Q

What processes does exercise influence in the body?

A

Regulates peripheral anti-inflammatory processes.

32
Q

What does exercise facilitate in terms of myokines?

A

Upregulation in IL-6 and growth factors that can pass the blood-brain barrier.

33
Q

What are some key myokines involved in exercise?

A

IL-6, IL-10, S-INH, TNF, Th1 (IFN-y), TLR expression.

34
Q

What type of stress is associated with adipose tissue?

A

Oxidative stress.

35
Q

What are the reported effects of exercise on the brain and CNS?

A

Exercise is reported to exert multiple beneficial effects in the brain and CNS, including increased grey matter volume and improved cognitive functioning.

36
Q

What cognitive functions are improved by exercise?

A

Exercise improves cognitive functioning, including working memory, social cognition, and attention.

(5)

37
Q

How does exercise influence neurogenesis?

A

Exercise influences neurogenesis and synaptic potentiation.

38
Q

What effect does exercise have on cerebral cytokines?

A

Exercise downregulates cerebral cytokines to reduce neuroinflammation.

39
Q

What is one long-term benefit of exercise related to degenerative diseases?

A

Exercise delays the onset of degenerative disease.

(7)

40
Q

What is the focus of the study by Dunleavy et al, 2022?

A

Investigating the effects of a 6-week moderate-to-vigorous exercise intervention on inflammatory biomarker concentration and negative symptom presentation in First Episode Psychosis.

41
Q

What questionnaire is used for screening negative symptoms?

A

Negative Symptom Questionnaire.

42
Q

What does FEP stand for?

A

First Episode Psychosis.

43
Q

What are the response options for the Negative Symptoms questionnaire?

A

Strongly agree, Agree, Disagree, Strongly disagree.

44
Q

What is the main focus of the study titled ‘ExerciseAPsychosis’?

A

The study assesses the effect of moderate-to-vigorous exercise on inflammatory biomarkers and negative symptom profiles in men with first-episode psychosis.

45
Q

How long was the exercise program in the study?

A

The exercise program lasted for 6 weeks.

46
Q

What intensity of exercise was used in the study?

A

Standardised exercise bouts were conducted at 60-75% of an individual’s personal HRMax.

47
Q

What significant changes were observed after the exercise program?

A

Significant changes in biomarkers and symptom profiles central to first-episode psychosis pathophysiology were observed.

48
Q

What specific biomarker showed significant reductions?

A

There were significant reductions in basal circulating IL-6 concentration.

49
Q

Which other biomarkers increased during the study?

A

Increases were seen in IL-8, IL-10, BDNF, and VEGF.

50
Q

What was the impact of the exercise on negative symptoms?

A

There was a significant reduction in negative symptoms and general psychopathology.

Flash Cards For Relevant Exam Rhematoid Arhritis (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions