Renal Phys ML: 5 Flashcards
Sodium processing
it is happening all the time due to intrinsic properties of the nephron
Sodium regulation
how other systems regulate sodium to meet homeostatic demand (extrinsic)
Where does the majority of water loss occur?
in the urine
True or false: for homeostasis to be maintained, intake must equal output
true
What is the main regulator for intake to match output
urine
When you intake excess water what does that do to the ISF concentration
makes it hypotonic meaning more water than solutes
The hypotonic ISF which is causes by intake of excess water, what does that do to the cell?
causes water to move into the hypertonic solution which is the cell
When you consume excess NaCl how does it get into the ISF
it diffusion across into the ISF which makes the soltuion hypertonic
When you consume excess NaCl why does water flow out of the cell and into the ISF
because the cell is not a hypotonic solution and water wants to dilute so it goes to the hypertonic solution
When water flows into the ISF what happens
increase plasma volume and MAP
How does the excess water distribute?
is distributed equally across all membranes but it is mainly in cells because that is where most of our fluid is
-2/3 in cells
-1/3 in isf
Where are Na+ and H20 freely filtered
at the glomerulus
What detects changes in the ECF
baroreceptors
What causes change in ecf volume?
gains in NaCl
What causes change in ecf osmolarity
changes in water
