Organic Metab ML: 3 Flashcards
Why does increased plasma glucagon stop hunger
part of the symp NS
Dietary changes to total body energy stores trigger what
negative feedback in energy expenditure
Decreased energys stores=
decreased metabolic rate
True or false; physical acitivty offsets change in metabolic rate
true
How is excercise state similar to the fasted state
need to provide glucose to body in large quantities without food
As you excercise what happens to your glucose and glucagon levels
glucose: decreases
glucagon: increased
Why is insulin down when we excercise
because we are increasing the sympathetic
-pro glucagon and ani insulin
Why does the the loss of insulin during excerise not affect muscle glucose uptake
because of internal glucose transporters
Type 1 diabetes mellitus
lack of insulin production (genetic)
Type 2 diabetes mellitus
lack of insulin sensitiivty at target cells
lack of insulin secretion from beta cells
What dies diabetic ketoacidosis most often occur
untrated type 1 diabetes
How does diabetic ketoacidosis affect renal function
increased glucose in filtrate disrupts the osmotic gradient which can lower plasma volume and hurt the brain
How does diabetic ketoacidosis affect pH balancing
decreased insulin= increased triglyceride breakdown which produces large quantities of acidic ketones