Organic Metab ML: 3 Flashcards

1
Q

Why does increased plasma glucagon stop hunger

A

part of the symp NS

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2
Q

Dietary changes to total body energy stores trigger what

A

negative feedback in energy expenditure

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3
Q

Decreased energys stores=

A

decreased metabolic rate

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4
Q

True or false; physical acitivty offsets change in metabolic rate

A

true

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5
Q

How is excercise state similar to the fasted state

A

need to provide glucose to body in large quantities without food

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6
Q

As you excercise what happens to your glucose and glucagon levels

A

glucose: decreases
glucagon: increased

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7
Q

Why is insulin down when we excercise

A

because we are increasing the sympathetic
-pro glucagon and ani insulin

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8
Q

Why does the the loss of insulin during excerise not affect muscle glucose uptake

A

because of internal glucose transporters

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9
Q

Type 1 diabetes mellitus

A

lack of insulin production (genetic)

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10
Q

Type 2 diabetes mellitus

A

lack of insulin sensitiivty at target cells
lack of insulin secretion from beta cells

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11
Q

What dies diabetic ketoacidosis most often occur

A

untrated type 1 diabetes

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12
Q

How does diabetic ketoacidosis affect renal function

A

increased glucose in filtrate disrupts the osmotic gradient which can lower plasma volume and hurt the brain

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13
Q

How does diabetic ketoacidosis affect pH balancing

A

decreased insulin= increased triglyceride breakdown which produces large quantities of acidic ketones

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