Renal Phys ML: 3 Flashcards
Amount of water filtered per day
180 L
Amount of water excreted per day
1.8L
Percent of water absorbed
99%
Amount of sodium filtered per day
630 g
Amount of sodium excreted per day
3.2 g
Percent of sodium absorbed
9.5%
Amount of glucose filtered per day
180 g
Amount of glucose excreted per day
0
Percent of glucose absorbed
100%
Amount of urea filtered per day
54g
Amount of urea excreted per day
30 g
Percent of urea reabsorbed
44%
What are the two modes of tubular reabsorption
diffusion- lipid soluble substances that dont need carriers
mediated transport: large/charged substances
Transcellular route
- apical (luminal) membrane
-basolateral membrane
-renal interstitial fluid - Peritubular capillaries
Paracellular route
-tight junctions
-renal interstitial fluid
-peritubilar capillaries
True or false; tight junctions vary by region
true
What happens when the max transport is reached for glucose absorption
starts showing up in the urine
Reabsorption keeps up with filtration at ____ plasma concentrations
low
Tubular secretion
from bloodstream to nephron
What substances use tubular secretion
foregin chemicals, drugs and toxins, hormones, breakdown products, organic wastes, H+ and K+
What moves in opposite directions during tubular secretion
transcellular and paracellular routes
Where does most secretion occur
proximal tubules
Where are K+ and H+ mainly secreted
cortical collecting duct
True or false: secreted substances have a transport maximum too
true
