Renal Phys ML: 2 Flashcards

1
Q

What percent of blood will flow through the afferent arteriole?

A

100%`

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2
Q

What percent of blood flows into the nephron?

A

20%

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3
Q

What percent of blood flows into the EA?

A

80%

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4
Q

Tubular reabsorption

A

the good substances that the body doesnt want to lose will be reabsorbed back into the capillary

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5
Q

Tubular Secretions

A

secreting undesirable substances into the nephron

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6
Q

Why does secretion not equal excretion

A

a change that substances can be reabsorbed back in

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7
Q

Drug and Toxin secretions

A

-freely filtered
-100% secreted
-undesirable substance

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8
Q

Na, Cl, Water secretions

A

-freely filtered
-partially reabsrobed

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9
Q

Glucose, Amino Acids

A

-freely filtered
-100% reabsorbed

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10
Q

Where does glomerular filtration take place?

A

renal corpuscle

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11
Q

Visceral layer of bowman’s capsule

A

podocute cells that are wrapped around the capillaries

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12
Q

How does the filtered blood leave bowmans capsule

A

proximal tubule

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13
Q

What do filtration slits allow

A

fluid to pass into bowman’s capsule

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14
Q

What are the three layers composing the filtration barrier

A
  1. capillary endothelium (fenestrated=more exchnage)
  2. Basement membrane (negatively charged matrix) shrink wrapped around capillary
  3. Bowman’s epithelium (podocutes and filtration slits)
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15
Q

What is filtrate

A

blood plasma except for RBCs and proteins

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16
Q

Why are there no RBC and proteins within the filtrate

A

-plasma proteins and cells too big for filtration
-negatively charged membrane exlcudes plasma proteins

17
Q

What is a normal GFR

A

125 mL/min

18
Q

Pgc

A

glomerular capillary pressure (60)

19
Q

What decreases GFR

A

-constrict AA
-dilate EA

20
Q

What increases GFR

A

-Constrict EA
-dilate AA

21
Q

What are the forces that favor filtration

A

Pgc= the pressure in the glomerlar capillaries will push filtrate into bowman’s space

22
Q

What forces oppose filtration?

A

Pbs= pressure of filtrate in bowmans space (15)
Pigs= osmotic force due to protein plasma (29)
-determined by plasma proteins

23
Q

Pgs___ to opposing forces then filtration into bowmans space can occur

A

> , this is normal

24
Q

FL>EL

A

net reabsorption

25
Q

FL<El

A

Net secretion