Renal Flashcards
Most common site of fetal obstruction
ureteropelvic junction
potters syndrome cause (limb/facial/pulmonary hypoplasia)
oligohydramnios
horseshoe kidney association
turner syndrome(under IMA)
clearance equation
UV/P
RBF equation
RPF/(1-Hct)
angiotensin II sites of action
efferent arteriole, ADH, NA-H exchange PCT(contraction alkalosis), AT1 vascular SM, aldosterone, hypothalamus
glucose clearance threshold
140
RAAS system sensors
JG cells=BP, macula densa=Na delivery
ANP mechanism
sense atrial pressure, relaxes SM via cGMP, Na loss
NSAIDs renal failure mechanism
inhibit prostaglandins that dilate afferent arteriole
anion gap
Na-(Cl+HCO3)>12, MUDPILES(normal=HARDASS)
fatty casts in urine
nephrotic syndrome
brown casts
tubular necrosis
waxy casts
chronic/advanced renal disease
nephrotic
proteinuria(>3.5), edema, fatty casts, hyperlipidemia
acetazolamide (CA inhibitor) use
altitude sickness/alkalosis/glaucoma
loop(furosemide/ethacrynic acid) toxicity
oto, low K, gout
thiazide MOA
Block DCT NaCl symporter
thiazide toxicity
hyperlipid/Ca/uric/glucose, low Na
Angiotensin II SE+mediator
dry cough& angioedema-bradykinin
polycystic kidney disease associations
hepatic fibrosis(autoRecessive), berry anyeurism(autoD)
Acute renal failure hallmark
azotemia, oliguria