Neuro Flashcards
Glioblastoma pathology
GFAP stained astrocytes
Neurofibromatosis gene
NF1 chromosome 17(neurofibromin tumor suppressor protein in myelin)
von-hippel lindau gene
VHL chromosome 3(autoD, tumor suppressor)
MS pathology
oligoclonal bands& periventricular plaques
Guillan-Barre causes
campylobacter jejuni, CMV& vaccines
Acute disseminated encephalomyelitis causes
measles, VZV& vaccines
Krabbe’s deficiency
galactocerebrisidase
metachromic leukodystrophy deficiency
arylsulfatase A
Alzheimers genes
presenilin, APP& ApoE4.
Alzheimers pathology
B-amyloid, tau protein& neurofibrillary tangles
Horner’s syndrome causes
pancoast tumor& brown sequard(above T1)
Friederich’s ataxia deficiency
frataxin
lateral hypothalamus
hunger center
ventromedial hypothalamus
satiety center
anterior hypothalamus
cooling&PS center
posterior hypothalamus
heating&sympathetic center
VPL
body sensation
VPM
face sensation
LGN
vision
MGN
hearing
VL
motor
parkinsons deposits
lewy bodies(a-synuclein)
parkinsons brain loss
substantia nigra pars compacta(dopaminergic)
Huntingtons genes
CAG repeats
huntingtons brain loss
caudate(GABAergic neurons)
kluver bucy lesion
amygdala
wernicke-korsakoff lesion
mammilary bodies(thiamine deficiency)
locked-in lesion
central pontine myelinosis
Berry anyeurism location
cicle of willis bifurcations
epidural hematoma
middle meningeal A(not X sutures)
subdural hematoma
bridging veins(crescent+X sutures)
subarachoid hemorrhage
berry anyeurism rupture
poliomyelitis lesion
anterior horn
werdnig-hoffman lesion
anterior horn
ALS common defect
superoxide dismutase 1
ALS lesion
UMN+LMN(no sensory, cognitive or oculomotor)
syringomyelia associated defect
chiari 1 malformation
B12/vitamin E deficiency lesion
dorsal columns+lateral CST+spinocerebellar
acoustic schwannoma association
neurofibromatosis type 2
schwannoma associated cell marker
s100
most common brain tumor
glioblastoma
hemangioblastoma association
von-hippel lindau disease
most common childhood brain tumor
craniopharyngioma
short procedure anesthetics
barbiturates(thiopental)& propofol
malignant hyperthermia treatment
dantrolene
Sign of neural tube defects
elevated AFP
sign of anencephaly
polyhydraminos
typical syringomyelia levels
C8-T1
friedrich’s ataxia association
hypertrophic cardiomyopathy
neonatal meningitis bugs
group B strep, listeria &Ecoli
infant meningitis
H influenza
adolescent/adult meningitis
neisseria M
most common viral meningitis
cocksackie
moderate brain ischemia lesions
cortical laminar necrosis, pyramidal neurons& cerebellar purkinje neurons
thrombotic stroke color
pale
embolic stroke characteristic
hemorrhagic
lacunar stroke vessels
lenticulostriate
ischemic stroke lesion
red neurons(liquefactive)
berry anyeurism associations
Marfan&ADPKD
multifocal leukoencephalopathy cause
JC virus
decreased risk of alzheimers gene
ApoE2
populations at risk for alzheimers
elderly&downs syndrome
Picks disease areas affected
frontal& temporal lobes
spongiform protein dysfunction
beta sheet prions
Guillian-Barre Tx
IVIG, plasmaphoresis, respiratory support
MS Tx
IFN-beta
Wilson’s Disease pathology
kaiser-fleischer rings
Gq phospholiase C receptors
M3, CCK-B
Gi adenyl cyclase receptors
somatostatin, PG
Gs adenyl cylase receptors
H2
stage I sleep waves
theta
stage 2 sleep waves
sleep spindles, k complex
stage 3 sleep waves
delta
REM sleep waves
beta
NF gene type
tumor suppresor
brain tumor with rounded cells+fine branching capillaries, frontal lobe
oligodendroglioma
right hemiparesis&proprioceptive loss, tongue deviates left
left medial medullary(ASA paramedian branches)
dysphagia, hoarseness, right horners, ataxia, decreased pain&temp
lateral medullary-wallenberg(PICA)
facial paralysis, nystagmus, right pain&temp/hearing loss&right horners
lateral pontine(AICA)