Embryo Flashcards
ototoxicity drugs
aminoglycosides(strep/tobra/neo/gentamicin/amikacin)
neural tube defect drugs
MTX/TMP, carbamazapine, valproic acid
discolored teeth drug
tetracycline(only RMSF in kids)
blood thinner during pregnancy
heparin(warfarin crosses placenta)
limb/digit defect drugs
thalidomide, alkylating agents(cyclophosphamide)
ebstein anomaly+drug
atrialized right ventricle-lithium
DES association
clear cell vaginal adenoma&mullerian abnormalities
Phenytoin effects
fetal hydantoin syndrome(IUGR/microcephaly/limb defects)
cocaine birth effects
placental abruption, addiction&abnormal developement
vitamin A in pregnancy
excess=spontaneous abortion/birth defects
pregnancy x-ray effects
microcephaly, retardation
maternal diabetes association
caudal regression syndrome(anal atresia), heart/neural tube defects
aortic arch derivatives
1=maxillary, 2=stape/hyoid, 3-carotid, 4-L=arch/ R=subclavian, 6=pulmonary arteries/L ductus arteriosus
branchial arch derivatives
1=mastication(treacher collins) V2/3, 2-facial-VII, 3-stylop-IX, 4-6=larynx/pharynx-X
branchial pouch derivatives
1-ear, 2-tonsils, 3-inf PT/thymus, 4-sup PT
testes determining factor
SRY gene(releases mullerian inhibitory factor/Test)
suspensory ligament of the ovaries vessels
ovarian(ureter at risk in oophorectomy)
cardinal ligament vessels
uterine(ureter at risk in hysterectomy)
spermatogenisis genetics
2ndary spermocyte&later= haploid, zoon=activated
oogenesis genetics
diploid until ovulation meiosis I, meiosis II-fertilization
pregnancy timeline
fertilize-1d after ovulation, 6d-implant, bHCG 1w in blood, 2w in urine
testicular atrophy, gynecomastia, female hair in a M
47XXY-klinefelters
web neck, short, infertile F
45X0 Turners syndrome
turners syndrome asspciations
coarctation of the aorta, horseshoe kidney, dysgerminoma
tall, antisocial &severe acne M
47XYY-double Y(normal fertility
anosmia+lack of secondary sex characteristics
Kallmen’s syndrome(defective GnRH migration)