Recurrent pregnancy loss (lecture)

Question 1

What is the most common reason for trisomy?

Answer 1

Nondisjunction during either meiosis 1 or 2

Question 2

What is the embryologic structure that forms the uterus? What 4 uterine malformations result in improper fusion?

Answer 2

Mullerian duct

- Spetate, unicornuate, bicornuate, didelphys

Question 3

What are the two acquired causes of anatomical abnormalities responsible for infertility covered in class?

Answer 3

Fibroids, Intrauterine adhesions

Question 4

What are the two immunologic reasons for recurrent pregnancy loss covered in class?

Answer 4

SLE and Antiphospholipid Antibody Syndrome

Question 5

What are the two treatment regiments for Antiphospholipid Antibody Syndrome?

Answer 5

ASA + Heparin or LMWH

Question 6

What type of birth defects are a/w Diabetes Mellitus?

Answer 6

Neural Tube

Question 7

What are the three environmental causes of recurrent pregnancy loss covered in class?

Answer 7

Smoking, ETOH, Caffeine use