Infertility Treatment (lecture) Flashcards
1
Q
What is the indication and MoA of Clomiphene Citrate?
A
Infertility - SERM that competes with central estrogen (no negative feedback from estrogen) and induces FSH / LH release and ovulation
2
Q
What is the first line treatment of postmenopausal estrogen positive breast cancer?
A
Letrozole
3
Q
What is the MoA of letrozole?
A
Inhibit aromatase in the ovary blocking estrogen production
4
Q
What is the first line treatment of infertility in polycystic ovarian syndrome?
A
Weight loss
5
Q
What two prescriptions are used in polycystic ovarian syndrome?
A
Clomiphene Citrate (first line) Metformin