Infertility Treatment (lecture) Flashcards

1
Q

What is the indication and MoA of Clomiphene Citrate?

A

Infertility - SERM that competes with central estrogen (no negative feedback from estrogen) and induces FSH / LH release and ovulation

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2
Q

What is the first line treatment of postmenopausal estrogen positive breast cancer?

A

Letrozole

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3
Q

What is the MoA of letrozole?

A

Inhibit aromatase in the ovary blocking estrogen production

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4
Q

What is the first line treatment of infertility in polycystic ovarian syndrome?

A

Weight loss

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5
Q

What two prescriptions are used in polycystic ovarian syndrome?

A
Clomiphene Citrate (first line)
Metformin
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