Recent Advances in Roles of Biomolecules in Biological Systems

Question 1

allow researchers to sequence single molecules of RNA without amplification.

Answer 1

third generation sequencing

Question 2

Some engineered biomolecules, including humanized ___, have already entered the clinical trials for therapeutic use

Answer 2

Mab’s

Question 3

a humanized Mab for breast cancer treatment, became the first drug designed by a biomolecular engineering approach and was approved by the FDA

Answer 3

Herceptin

Question 4

New metabolites, including novel antibiotics that are active against resistant strains, will also be produced soon by recombinant organisms having

Answer 4

de novo engineered biosynthetic pathway

Question 5

allows for the visualization of biomolecules at the nanometer scale.

Answer 5

scanning probe microscopy

Question 6

is crucial for gaining a comprehensive understanding of the properties and functions of biological systems at the most fundamental level.

Answer 6

imaging biomolecules

Question 7

provides a powerful and nondestructive imaging optio

Answer 7

scanning probe microscopy

Question 8

SPM is unique in visualizing intrinsically disordered biomolecules at the what meter scale (e.g., glycans).

Answer 8

nanometer

Question 9

These sensors can detect biological molecules, bacteria, and cells. They are low cost, fast, and easy to use.

Answer 9

electrochemical biosensors

Question 10

has become an attractive material in the field of electrochemical detection owing to its unique electrical properties

Answer 10

graphene

Question 11

Nucleic acids can be used to form 3-dimensional ___ ___that can be tagged with biological and therapeutic compounds.

Answer 11

nano-scaffolds

Question 12

an also be formulated from nucleic acids strands of DNA and RNA

Answer 12

nanoparticles

Question 13

he current research in the development of bio-based nanoparticles have shown that the DNA and RNA nanoparticles can be utilised as ___ and can be tagged with various types of biological and therapeutic compounds such as aptamers, fluorophores, and oligonucleotides to carry its desired function

Answer 13

scaffolds

Question 14

he current research in the development of bio-based nanoparticles have shown that the DNA and RNA nanoparticles can be utilised as scaffolds and can be tagged with various types of biological and therapeutic compounds such as ___ ___ ___

Answer 14

aptamers
fluorophobes
oligonucleotides

Question 15

what sensing surfaces can be used to access biomolecular interactions

Answer 15

silver
copper
higly ordered pyrolytic graphite

Question 16

appears as an invaluable experimental technique, allowing the measurement of the mechanical strength of biomolecular complexes to provide a quantitative characterization of their interaction properties from a single molecule perspective.

Answer 16

atomic force microscopy

Question 17

can be used to deliver biomolecules and drugs to cancer cells.

Answer 17

metal-organic frameworks

Question 18

in general, have been extensively used for the delivery and protection of biomolecule

Answer 18

metal organif frameworks

Question 19

can interact with protein, nucleic acids and peptides and act as solid supports for bio-entities, enhancing their stability and their biological activity

Answer 19

metal organic frameworks