[RECALLS] Plasma Proteins And Ig; Purine And Pyrimidine Biosynthesis Flashcards

1
Q

Attaches on surface of mast cells

A

IgE

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2
Q

Active during allergic response

A

IgE

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3
Q

Most abundant plasma protein

A

Albumin

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4
Q

Binds to ffa, calcium, some copper and bilirubin

A

Albumin

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5
Q

Both monomer and dimer

A

IgA

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6
Q

Low levels during hemolytic anemia

A

Haptoglobin

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7
Q

Transports iron to where it is needed

A

Transferrin

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8
Q

Carries iron across basolateral membrane

A

Ferroportin

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9
Q

Main copper transporter in plasma

A

Ceruloplasmin

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10
Q

Mutated copper binding p-type atpase in wilsons disease

A

ATP7B

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11
Q

Found in secretions

A

IgA

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12
Q

Ig mainly for secondary immune response

A

IgG

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13
Q

Ig mainly for primary immune response

A

IgM

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14
Q

This is found in the surface of B cell that binds to antigen

A

IgD

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15
Q

Separation technique where proteins migrate to one side

A

Electrophoresis

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16
Q

Plasma protein that migrates to gamma region during electrophoresis

A

Immunoglobulins

17
Q

Mitochondrial enzyme

A

Carbamoyl phosphate synthase I

18
Q

Which one is not a multifunctional enzyme

A

PRPP Glutamyl amidotransferase

19
Q

Treatment for acute gout

A

Cholicine

20
Q

Deficiency in Von Gierke’s

A

Glucose 6 phosphate

21
Q

Which is true about purine biosynthesis

A

Phosphoribosyl pyrophosphate- 1st intermediate in denovo pathway

22
Q

Major determinant of overall rate

A

PRPP pool size

23
Q

1st product in pyrimidine is recycled to form

A

Cytidine and uridine

24
Q

First pyrimidine formed

A

UMP

25
Q

All synthesized in the liver except

A

Gamma globulin

26
Q

Preferred locus target for gout

A

Xanthine oxidase

27
Q

Lesch nyhan syndrome

A

HGPRT deficiency

28
Q

ADA deficiency results in accumulation of

A

Deoxyadenosine and adenosine

29
Q

Parent nucleotide of AMP and GMP

A

IMP

30
Q

Non-multifunctional purine enzyme catalyzed

A

Reaction 5