[RECALLS] Plasma Proteins And Ig; Purine And Pyrimidine Biosynthesis Flashcards
Attaches on surface of mast cells
IgE
Active during allergic response
IgE
Most abundant plasma protein
Albumin
Binds to ffa, calcium, some copper and bilirubin
Albumin
Both monomer and dimer
IgA
Low levels during hemolytic anemia
Haptoglobin
Transports iron to where it is needed
Transferrin
Carries iron across basolateral membrane
Ferroportin
Main copper transporter in plasma
Ceruloplasmin
Mutated copper binding p-type atpase in wilsons disease
ATP7B
Found in secretions
IgA
Ig mainly for secondary immune response
IgG
Ig mainly for primary immune response
IgM
This is found in the surface of B cell that binds to antigen
IgD
Separation technique where proteins migrate to one side
Electrophoresis
Plasma protein that migrates to gamma region during electrophoresis
Immunoglobulins
Mitochondrial enzyme
Carbamoyl phosphate synthase I
Which one is not a multifunctional enzyme
PRPP Glutamyl amidotransferase
Treatment for acute gout
Cholicine
Deficiency in Von Gierke’s
Glucose 6 phosphate
Which is true about purine biosynthesis
Phosphoribosyl pyrophosphate- 1st intermediate in denovo pathway
Major determinant of overall rate
PRPP pool size
1st product in pyrimidine is recycled to form
Cytidine and uridine
First pyrimidine formed
UMP
All synthesized in the liver except
Gamma globulin
Preferred locus target for gout
Xanthine oxidase
Lesch nyhan syndrome
HGPRT deficiency
ADA deficiency results in accumulation of
Deoxyadenosine and adenosine
Parent nucleotide of AMP and GMP
IMP
Non-multifunctional purine enzyme catalyzed
Reaction 5
