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2ND SEM BIOCHEMISTRY > [RECALLS] Ig and Porphyrin - Batch 2022 > Flashcards

[RECALLS] Ig and Porphyrin - Batch 2022 Flashcards

1
Q

Bilirubin found on bile ductules

A

Bilirubin diglucoronides

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2
Q

Direct measurement of CO

A

Heme oxygenase

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3
Q

Ferroxidase activity

A

Ceruloplasmin or haphaestin

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4
Q

Exhibits polymorphism except

A

Ferritin

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5
Q

Total protein in human plasma (g/dL)

A

7.0 - 7.5

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6
Q

Characterized by profound neurologic impairments

A

Zellweger syndrome

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7
Q

Rapid formation and reshuffling of disulfide bonds

A

PDI

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8
Q

Ubiquitin

A

4

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9
Q

Sugar in nucleotide

A

Pentose

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10
Q

Colorless

A

Urobilinogen

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11
Q

Ig is kappa or lambda, never mixed:

A

True

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12
Q

5 phosphoryl group esterify 2nd hydroxyl group

A

Phosphodiester

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13
Q

Phosphoryl group linked to the phosphoryl group of a mononucleotide

A

Acid anhydride bond

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14
Q

From the mitochondria, outer membrane receptor

A

TOM 20./22

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15
Q

Proteins are transferred to this neighboring import channel

A

TOM 40

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16
Q

Repository of heme

A

RBC

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17
Q

Important element in body cause seen in hemoprotein

A

Iron

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18
Q

From apical surface to interior

A

DMT1

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19
Q

Ferric to ferrous

A

Ferrireductase

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20
Q

Bidirectional movement along nucleus and cytoplasm

A

Ran protein

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21
Q

True about signal peptide

A

At least 1 positive charge etc

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22
Q

Primary immune response

A

IgM

23
Q

Nucleoside

A

Guanosine

24
Q

Main antibody in secondary response. Opsomizes bacteria

A

IgG

25
Q

Found on surfaces of B cells as a receptor for antigen

A

IgD

26
Q

Function of Ig other than direct binding of antigen

A

Fc

27
Q

Physiologic functions of nucleotides except

A

Energy metabolism

28
Q

True of bilirubin except

A

Bound to albumin thru non covalent forces increases plasma solubility

29
Q

Hydrostatic pressure of arterioles

A 
37 mmHg (Book)
40 mmHg (ppt)
30
Q

Involved in intra-GA transport & retrograde transport from the GA to the ER

A

COP I

31
Q

Involved in export from the ER to either ERGIC or the GA

A

COP II

32
Q

Transport in post-GA locations including the PM, TGN and endosomes

A

Clathrin

33
Q

Regulated secretion from organs such as the pancreas

A

Secretory vesicles

34
Q

Carry proteins to the PM & are also involved in constitutive secretion

A

Vesicles from the TGN to the PM

35
Q

Low PO2 in peripheral tissues causes synthesis of:

A

2,3 - BPG

36
Q

Direct measurement of CO

A

Heme oxygenase

37
Q

Colourless compound

A

Urobilinogen

38
Q

Colored compound found in feces

A

Stercobilin

39
Q

Porphyrin ring

A

Hydrophobic

40
Q

Blue-green color

A

Biliverdin

41
Q

What happens to albumin when removed from bilirubin

A

Remains in plasma

42
Q

Location of heme oxygenase

A

Endoplasmic reticulum

43
Q

Conjugation of bile is catalyzed by

A

UDP-Glucoronyl transferase

44
Q

Has large capacity that even under the pathologic conditions, transport does not appear to be rate-limiting for metabolism of bilirubin

A

Facilitated transport system

45
Q

Derivatives of purine and pyrimidine that has a sugar-linked to a ring N

A

Nucleosides

46
Q

Sugar is linked to a heterocyclic base via

A

B.N-glycosidic bond

47
Q

True of a sugar that is linked to heterocyclic base

A

Pyrimidine at N1 ; purine at N9

48
Q

Nucleoside with a phosphoryl group esterified to OH group of sugar

A

Mononucleotide

49
Q

Free nucleotides

A

Xanthine
Hypoxanthine
Uric acid

50
Q

Function of purines and pyrimidines

A

High group transfer potential

51
Q

Nucleoside derivative of guanine

A

Guanosine

52
Q

True about P50 except:

A

PO2 half saturates myoglobin

53
Q

5’ end on the

A

Left

2ND SEM BIOCHEMISTRY (33 decks)

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