[Recalls] Myoglobin And Hemoglobin, Porphyrin, Bilirubin, Nucleoside Flashcards
Methemoglobin
Ferric ion
Guanine and adenine free nucleotides
Hypoxanthine, xanthine and uric acid
N1
Pyrimidine
N9
Purine
Wrong statement
Release of 02 from myoglobin na at 20 mmHg tissue
*Must be 5 mmHg
Mononucleotides
Phosphoryl group esterified to hydroxyl group
Anhydride bond
Nucleoside di/triphosphate
Nucleoside triphosphate
High group transfer potential
Fetal Hgb
2 alpha
2 gamma
Physiologic function of nucleotides except:
Carboxylation and deamination
Sugar linked to heterocyclic base
B-N glycosidic bond
Phosphodiester bond
Nucleotides
Example of nucleoside
Guanosine
Increase in O2 binding if there is an O2 bound already
Cooperative binding
ALA -> PBG
ALA dehydratase
Porphyrin ring
Hydrophobic
Heme oxygenase
ER
CO content of expired air
Heme oxygenase
UDP glucoronyl transferase
Bilirubin conjugation
Biliverdin
Blue green
Facilitated transport system
Hepatocellular uptake
What will happen to albumin after transporting?
Remains in plasma
Repository site of heme
RBC
Iron porphyrin degradation
Liver
Thalassemia
Imbalance of globin chain synthesis
Hb M
His F8 replaced by tyrosine
Bohr effect
Protons and pH
5th His residue
Prox His F8
Colorless
Urobilinogen
Color of feces
Stercobilin
Relaxed state except
D
Deoxygenated state
Fe2+ out of plane
P50 concept
PO2 that saturates 50 and Hgb
Hypoxic tissues will trigger the production of:
2,3 DPG
Sugar attached to base
Nucleoside