Nomenclature Of Enzymes - Dr. Bonleon Flashcards
Involved in oxidation and reduction.
Oxidoreductase
Loss of electrons
Oxidation
Gain of electrons
Reduction
Use O2 as an e- acceptor but do not incorporate into the substrate.
Oxidases
Use molecules other than O2 (e.g NAD+) as an e- acceptor.
Dehydrogenases
Directly incorporate O2 into the substrate.
Oxygenases
Use H2O2 as an e- acceptor.
Peroxidases
Catalyze transfer of groups such as METHYL or GLYCOSYL groups from a donor molecule to an acceptor molecule.
Transferases
Transfer functional or chemical groups (amino or phosphate groups)
Transferases
Transfer 1-C units between substrates.
Methyltransferases
Transfer NH2 from amino acids to ketoacids.
Aminotransferases
Transfer PO3- from ATP to a substrate.
Kinases
Transfer PO3- from Pi to a substrate.
Proteases
Catalyze the hydrolytic cleavage of C-C, C-O, C-N, C-P or certain other bond, including acid anhydride bonds.
Hydrolases
Transfer water.
Hydrolases
Add or remove H2O from molecules.
Hydrolases
Catalyze the hydrolysis of a substrate.
Hydrolases
Remove PO3- from a substrate.
Phosphatases
Cleave phosphodioester bonds such as those in nucleic acids.
Phosphodiesterases
Cleave amide bonds such as those in proteins.
Proteases
Catalyze the cleavage of C-C, C-O, C-N and other bonds by elimination, leaving double bonds and also add groups to double bonds.
Lyases
Add or remove the elements of water, ammonia or CO2 to (or from) double bonds.
Lyases
Manipulate double bonds by elimination reactions.
Lyases
Produce CO2 via elimination reactions.
Decarboxylases
Proupduce aldehydes via elimination reactions.
Aldolases
Link 2 molecules without involvement of ATP
Synthases
Catalyze geometric or structural changes within a single molecule.
Isomerases
Catalyze rearrangement of atoms within a molecule.
Isomerases
Interconvert L and D steroisomers
Racemases
Transfer groups between atoms within a molecule.
Mutases
Catalyze the joining together of 2 molecules, coupled to the hydrolysis of a pyrophosphoryl group in ATP or a similar nucleoside triphosphate.
Ligases
Condense C - (S/N/C/O) bonds using energy from ATP.
Ligases
Use CO2 as a substrate.
Carboxylases
Link 2 molecules via an ATP-dependent reaction.
Synthetases