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MRCOG part 1 > Recalls 5 > Flashcards

Recalls 5 Flashcards

1
Q

What type of drug is methyldopa

A

Alpha 2 adrenergic AGONIST

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2
Q

AGONISTS and ANTAGONISTS

A

Agonists:
Morphine (Mu)
Benzos (GABA)
Methyldopa (alpha 2 adrenergic)
Cabergoline (dopamine)
Mirabegron (B3 adrenergic)
Salbutamol (B1 and B2)

Antagonists:
Metoclopramide (dopamine)
Labetalol (A1and B1)
Atenolol (B1)
Tolterodine (muscarinic)
Ranitidine (H2)
Doxazocin (A1 adrenergic)

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3
Q

What type of drug is Zidovudane

A

Reverse transcriptase inhibitor

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4
Q

What is the main side effect of Dinoprostone

A

Fever

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5
Q

What is the remnant of the mesonephric tubules

A

epoophoron

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6
Q

Chromosome with centromere at one end?

A

It will be acrocentric because telocentric are nto available in humans

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7
Q

Which molecules are transferred across the placenta by:

Active transport
Passive diffusion
Facilitated diffusion
Pinocytosis

A

Active transport - Amino acids, Ca/Phos/Mg, Iron/iodine
Passive diffusion - urea, oxygen/CO2, free fatty acids, water
Facilitated diffusion - glucose
Endocytosis - Pinocytosis is IgG

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8
Q

With irregular cycles, how can you figure out when ovulation is

A

The luteal phase is always 14 days so in 25 day cycle it would be day 11

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9
Q

Most likely kareotype for partial mole

A

XXY - more likely to be egg + 2 independant sperm than egg + sperm that duplicates

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10
Q

Why not to give dextrose IV in HG

A

Increases demand for vitamin B1 with glucose administration so increases chance of Wericke’s encephalopathy

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11
Q

What type of drugs are:

Cyclizine
Ondansetron
Metoclopramide
Prochlorperazine
Promethazine

A

Cyclizine - H1 antagonist
Ondansetron - serotonin antagonist
Metoclopramide - dopamine antagonist - H1 antagonist
Prochlorperazine - dopamine antagonist
Promethazine

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12
Q

Process happening during pregnancy which means brest feeding can happen

A

lobular hyperplasia

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13
Q

Contrast chancre and chancroid

A

Chancre - hard edges, painless

Chancroid - soft edges, painless

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14
Q

When should the prophylactic and therapeutic doses of LMWH be stopped prior to regional anaesthesia

A

prophylactic - 12h

therapeutic - 24h

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15
Q

Mode of inheritance for BRCA

A

AD

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16
Q

What type of drug is:
neostigmine
Vidovudane
Warfarin/coumarin
Ramipril
Celeboxib
Aciclovir

A

Neostigmine - Anticholinesterase inhibitor
Vidovudane - Reverse transcriptase inhibitor
Warfarin - Vit K antagonist
Ramipril - ACE-i
Celeboxib - COX 2 inhibitor
Aciclovir - HSV specific thymadine kinase inhibitor

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17
Q

Which aortic arch is the ligamentum arteriosum a remnant of

A

6th aortic arch

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18
Q

How much millisievert is in CT chest vs CT abdo

A

CT chest - 7msv
Abdo CT - 10-15msv

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19
Q

Regarding breech, what is the bitrochanteric diameter?

What are the diameters of Vertex, OP, Brow and face

A

10cm

Vertex = 9.5
OP = 11
Brow = 13
Face = 9.5

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20
Q

What is the most common inherited bleeding disorder

A

VWD

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21
Q

What does Parvovirus B19 cause

A

Fetal anaemia
Hydrops
9% risk of loss

22
Q

What is anaemia defined as in first, second and portpartum

A

First <110

Second <105

PP <100

23
Q

Label this

A
24
Q

What is evidence based medicine

A

Using current clinical evidence to treat individual patients

25
Q

What does hypothyroidism do to LH FSH and TSH

A

high TSH

Low LH and FSH because low circulating levels of T3/4 lead to lower levels of those

26
Q

Which clotting factors do not change in pregnancy?

Which ones decrease?

A

Do not change = 2,5,9

Decrease = 11,13

27
Q

Which cells secrete histamine and serotonin

A

Mast cells and Basophils

28
Q

Label this

A
29
Q

When is the incubation period and the infective period of VZV

A

Incubation - 10-21 days
Infective - 2 days before the rash and until lesions crusted over

30
Q

What type of variable is gestational age

A

Interval

31
Q

Which is the safest type of electrical circuit in theatres

A

isolated

32
Q

What is the deep circumflex iliac artery a branch of?

What about the superficial?

A

The external iliac artery

The femoral artery

33
Q

Which essential amino acid not in omega 3 must be taken in via the diet

A

Histidine

34
Q

What is cervical cancer incidence in uk

A

1/3000

35
Q

What is used to determine receptor status of breast ca

A

immunohistochermistry staining

36
Q

What causes grey baby syndrome

A

chloramphenicol

37
Q

What is used for DNA amplofication

A

PCR

38
Q

What is the sensory supply to the cervix for a smear test

A

pelvic splanchnic

39
Q

What is the function of:

DNA polymerase
RNA polymerase
Reverse transcriptase
Helicase
DNA ligase

A

DNA polymerase - DNA replication

RNA polymerase - builds RNA from DNA

Reverse transcriptase - converts RNA into DNA

Helicase - unwind DNA and RNA

DNA ligase - joins DNA fragments together

40
Q

What is the direct blood supply to the decidua?

A

Spiral arteries

41
Q

What is the component of the placental barrier at term

A

syncytiotrophoblast and endothelium

42
Q
A
43
Q

Which neurotransmitter is secreted into the adrenal medulla

A

Acetylcholine

44
Q

What is type 1 an type 2 error

A

Type 1 = null hypothesis is correct and incorrectly rejected

Type 2 = null hypothesis is incorrect and incorrectly accepted

45
Q

How do you work out the % of obese people if the mean is 25 and the SD is 5

A

Well the SD 1+- above and below the mean is 68%. Therefore between 20-30 is 68%. There is 32 outside of this and therefore 16% obese people

46
Q

In multiparous women with prolapse, which muscle is most likely to be injuryed

A

pubococcygeus

47
Q

Where is the primary site of ammonioa production

A

The liver

48
Q

What is the most common benign ovarian tumour

A

benign teratoma

49
Q

What level would you expect a ureteric stone to be if the patient has groin pain

A

pelvic brim - where it crosses the iliacs

50
Q

Which structure produces inhibin

A

Granulosa cells

51
Q

How do you work out the EDD from first day LMP

A

Start with first day LMP
Add 1 year
Minus 3 months
Add 7 days

MRCOG part 1 (28 decks)

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