RBC Pathology Flashcards
1
Q
Acanthocyte
A
“spur cell”
- Liver disease
- Abetalipoproteinemia (states of cholesterol dysreg)
2
Q
Basophilic stippling
A
- Pb
- sideroblastic anemia
- myelodysplastic syndromes
3
Q
Dacrocyte
A
“teardrop cell”
- bone marrow infiltration (myelofibrosis)
4
Q
Degmacyte
A
“bite cell”
- G6PD deficiency
5
Q
Echinocyte
A
“burr cell” (smaller and more uniform projections than spur acanthrocytes)
- End-stage renal disease
- Liver disease
- pyruvate kinase disease
6
Q
Ringed sideroblast
A
- sideroblastic anemia
- excess iron in mitochondria
7
Q
Schistocyte
A
- DIC
- TTP/HUS
- HELLP syndrome
- mechanical hemolysis (heart valve)
8
Q
Spherocyte
A
- hereditary spherocytosis
- hemolysis (drug or infection-induced_
9
Q
Target cell
“HALT” said the hunter to this TARGET
A
HbC disease
Asplenia
Liver disease
Thalassemia
10
Q
Heinz bodies
A
Hb precipitation from oxidation of -SH groups on hemoglobin
- G6PD def
11
Q
Howell-Jolly bodies
A
Nuclear remnants in RBCs
- asplenia
